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TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339194(CHEMBL1689456)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339191(CHEMBL1689460)
Affinity DataKd:  4nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339192(CHEMBL1689461)
Affinity DataKd:  200nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339193(CHEMBL1689463)
Affinity DataKd:  5nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339195(CHEMBL1689464)
Affinity DataKd:  8nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339196(CHEMBL1689465)
Affinity DataKd:  5nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339197(CHEMBL1689466)
Affinity DataKd:  4nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339198(CHEMBL1689467)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339199(CHEMBL1689468)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339200(CHEMBL1689469)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339201(CHEMBL1689470)
Affinity DataKd:  9nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339202(CHEMBL1689471)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339203(CHEMBL1689472)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339204(CHEMBL1689473)
Affinity DataKd:  6nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339205(CHEMBL1689474)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339206(CHEMBL1689475)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339207(CHEMBL1689476)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339208(CHEMBL1689477)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339209(CHEMBL1689479)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339210(CHEMBL1689481)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339211(CHEMBL1689482)
Affinity DataKd:  8nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339191(CHEMBL1689460)
Affinity DataKd:  100nMAssay Description:Binding affinity to human PlGF-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339191(CHEMBL1689460)
Affinity DataKd:  400nMAssay Description:Binding affinity to mouse PlGFMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  9nMAssay Description:Binding affinity to human PlGF-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  70nMAssay Description:Binding affinity to mouse PlGFMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118029(3-Isopropyl-1-methanesulfonyl-4-(4-piperidin-1-yl-...)
Affinity DataKon:  2.06E+6M-1s-1pH: 7.4Assay Description:Association rate constant at pH 7.4.against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118029(3-Isopropyl-1-methanesulfonyl-4-(4-piperidin-1-yl-...)
Affinity DataKoff:  6.63E+3s-1pH: 7.4Assay Description:Dissociation rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118028(3-Isopropyl-1-methanesulfonyl-4-(2-pyrrolidin-1-yl...)
Affinity DataKoff:  3.05E+4s-1pH: 7.4Assay Description:Dissociation rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118027(4-[1-(2,2-Dimethyl-propyl)-azetidine-3-carbonyl]-3...)
Affinity DataKon:  1.09E+7M-1s-1pH: 7.4Assay Description:Association rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118030(4-(5-Cyclopropylaminomethyl-pyrazine-2-carbonyl)-3...)
Affinity DataKon:  3.30E+6M-1s-1pH: 7.4Assay Description:Association rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118030(4-(5-Cyclopropylaminomethyl-pyrazine-2-carbonyl)-3...)
Affinity DataKoff:  2.52E+5s-1pH: 7.4Assay Description:Dissociation rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50096484((4S,6R)-6-Allyl-4-(naphthalene-2-sulfonyl)-5-oxo-h...)
Affinity DataIC50: 0.0360nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50066997(CHEMBL2367632 | (3aS,6R)-6-Allyl-4-methanesulfonyl...)
Affinity DataIC50: 0.0470nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.100nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to rat pancreas cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005463(1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-phen...)
Affinity DataIC50: 0.100nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to rat pancreas cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005463(1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-phen...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50033600(Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 | CHEMBL...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339214(CHEMBL1689480)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50033586(3-[2-[(Adamantane-2-carbonyl)-amino]-3-(1H-indol-3...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.300nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex Cholecystokinin type B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50033600(Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 | CHEMBL...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50456331(CHEMBL2111203)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlacenta growth factor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50456329(CHEMBL2111261)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50033587([1-(1-Hydroxymethyl-2-phenyl-ethylcarbamoyl)-2-(1H...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50096486(benzyl (3aS,6aR)-4-acetyl-6-allyl-5-oxohexahydropy...)
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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