Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 3271 with Last Name = 'woolford' and Initial = 'aj'
TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125265(CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...)
Affinity DataIC50:  0.0350nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125265(CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...)
Affinity DataIC50:  0.0490nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125265(CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...)
Affinity DataIC50:  0.0490nMAssay Description:Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125265(CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...)
Affinity DataIC50:  0.0490nMAssay Description:Inhibition of recombinant human Lp-PLA2 incubated for 20 mins by Thio-PAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50573875(CHEMBL4869086)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full-length human N-terminal MAHHHHHH tagged-ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418177(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full-length human N-terminal MAHHHHHH tagged-ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418177(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.10nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418177(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.10nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418281((2R)-2-[6-(5-chloro-2-{[(2S)-1- hydroxypropan-2-yl...)
Affinity DataIC50:  1.20nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418281((2R)-2-[6-(5-chloro-2-{[(2S)-1- hydroxypropan-2-yl...)
Affinity DataIC50:  1.20nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417954(US10457669, Example 615)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418188(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417999(US10457669, Example 675 | US11001575, Example 675)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417999(US10457669, Example 675 | US11001575, Example 675)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417999(US10457669, Example 675 | US11001575, Example 675)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of full-length human N-terminal MAHHHHHH tagged-ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417953(US10457669, Example 614 | US11001575, Example 616)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418188(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418230((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418230((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418223((2R)-2-(3-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50:  1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182422(CHEMBL3818650)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418223((2R)-2-(3-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50:  1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418307((2R)-2-(6-}5-chloro-2-[(oxetan-3- yl)amino]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418305((2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)am...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418305((2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)am...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418266((2R)-2-(6-{5-chloro-2-[(1-methyl-1H- 1,2,3-triazol...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418229((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418266((2R)-2-(6-{5-chloro-2-[(1-methyl-1H- 1,2,3-triazol...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418229((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418307((2R)-2-(6-}5-chloro-2-[(oxetan-3- yl)amino]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418308((2R)-2-[6-(5-chloro-2-{[cis-3- methoxycyclobutyl]a...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418300((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418300((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418298((2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)am...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418133((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418200((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418276((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418200((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418133((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM497509(2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin-4- y...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418298((2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)am...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418308((2R)-2-[6-(5-chloro-2-{[cis-3- methoxycyclobutyl]a...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417711(2-(6-{5-bromo-2- [(oxan-4- yl)amino]pyrimidiin-4- ...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418276((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM417812(US10457669, Example 450)
Affinity DataIC50:  1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418089((2R)-2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl...)
Affinity DataIC50:  1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM418105((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50:  1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


Displayed 1 to 50 (of 3271 total ) | Next | Last >>
Jump to: