Compile Data Set for Download or QSAR
Report error Found 1044 with Last Name = 'wroblewski' and Initial = 'jt'
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181745(3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181745(3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181753(US8609852, 78 | CHEMBL202307 | 3-[(2-methyl-4-thia...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143073((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  0.900nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181745(3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...)
Affinity DataIC50: 0.940nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181753(US8609852, 78 | CHEMBL202307 | 3-[(2-methyl-4-thia...)
Affinity DataKi:  1.00nMAssay Description:Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM17659(pentanedioic acid analogue, (RS)-1 | 2-(phosphonom...)
Affinity DataKi:  1.40nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160633(2-methyl-6-[(5-phenylpyridin-3-yl)ethynyl]pyridine...)
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181753(US8609852, 78 | CHEMBL202307 | 3-[(2-methyl-4-thia...)
Affinity DataIC50: 2.01nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143074((S)-2-[3-((S)-Carboxy-phenyl-methyl)-ureido]-penta...)
Affinity DataKi:  2.10nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143078((S)-2-{3-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethyl...)
Affinity DataKi:  3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160632(3-(6-Methyl-pyridin-2-ylethynyl)-benzonitrile | 3-...)
Affinity DataIC50: 5nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  5.10nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM17659(pentanedioic acid analogue, (RS)-1 | 2-(phosphonom...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143070((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...)
Affinity DataKi:  5.30nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143080((S)-2-{3-[(S)-Carboxy-(4-hydroxy-phenyl)-methyl]-u...)
Affinity DataKi:  5.90nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160627(2-{[5-(2-furyl)pyridin-3-yl]ethynyl}-6-methylpyrid...)
Affinity DataKi:  6.5nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102256(2-[3-(1-Carboxy-2-mercapto-ethyl)-ureido]-pentaned...)
Affinity DataIC50: 6.90nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50123005(2-(3-Methoxy-phenylethynyl)-6-methyl-pyridine | 2-...)
Affinity DataIC50: 8nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181778(2-(4-fluorophenyl)-5-[(2-methyl-4-thiazolyl)ethyny...)
Affinity DataIC50: 10.2nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143069((S)-2-[3-((S)-1-Carboxy-2-phenyl-ethyl)-ureido]-pe...)
Affinity DataKi:  12nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160625(2-Methyl-6-(3-nitro-phenylethynyl)-pyridine | CHEM...)
Affinity DataIC50: 13nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160624(6-Methyl-5''-(6-methyl-pyridin-2-ylethynyl)-[2,3''...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143066((2S,5S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-urei...)
Affinity DataKi:  14.4nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143068((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  14.9nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181785(3-ethynyl-5-[(2-methyl-4-thiazolyl)ethynyl]pyridin...)
Affinity DataIC50: 19.2nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160633(2-methyl-6-[(5-phenylpyridin-3-yl)ethynyl]pyridine...)
Affinity DataIC50: 20nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102259(2-[(2,4-Dicarboxy-butyl)-hydroxy-phosphinoylmethyl...)
Affinity DataIC50: 21.7nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181748(4-(2-(3-fluorophenyl)ethynyl)-2-methylthiazole | C...)
Affinity DataIC50: 23nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181759(4-(3,5-difluorophenylethynyl)-2-methylthiazole | C...)
Affinity DataIC50: 25.3nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102255(2-[3-(2-tert-Butylsulfanyl-1-carboxy-ethyl)-ureido...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  35nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataIC50: 36nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160640(2-(3-Furan-2-yl-phenylethynyl)-6-methyl-pyridine |...)
Affinity DataKi:  36nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181749(4-(2-methoxyphenylethynyl)-2-methylthiazole | CHEM...)
Affinity DataIC50: 36.3nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataIC50: 39nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181742(2-chloro-3-[(2-methyl-4-thiazolyl)ethynyl]pyridine...)
Affinity DataIC50: 45.5nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102257(2-[3-(1,2-Dicarboxy-ethyl)-ureido]-pentanedioic ac...)
Affinity DataIC50: 46.1nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181739(4-(3-methoxyphenylethynyl)-2-methylthiazole | CHEM...)
Affinity DataIC50: 49nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181777(3-bromo-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine ...)
Affinity DataIC50: 60nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181746(3-[5-[(2-methyl-4-thiazolyl)ethynyl]-3-pyridyl]-2-...)
Affinity DataIC50: 68.6nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50160631(2-{[5-(3-methoxyphenyl)pyridin-3-yl]ethynyl}-6-met...)
Affinity DataKi:  74nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181770(4-(3-fluorophenylethynyl)-2-thiazolylamine | CHEMB...)
Affinity DataIC50: 78.6nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50149802(2-Methyl-4-m-tolylethynyl-thiazole | 2-methyl-4-(m...)
Affinity DataIC50: 82.6nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143064((2S,5R)-2-Benzyl-4-[3-((S)-3-carboxy-1-carboxy-pro...)
Affinity DataKi:  95.3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181779(4-(3-chlorophenylethynyl)-2-methylthiazole | CHEMB...)
Affinity DataIC50: 129nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181780(4-(2-fluorophenylethynyl)-2-methylthiazole | CHEMB...)
Affinity DataIC50: 140nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 1044 total ) | Next | Last >>
Jump to: