Compile Data Set for Download or QSAR
maximum 50k data
Found 43 with Last Name = 'wyman' and Initial = 'b'
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50:  26nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132421(3-[1-(1H-Pyrrol-2-yl)-meth-(Z)-ylidene]-5-(thiophe...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132420(3-((1H-pyrrol-2-yl)methylene)-5-(pyridin-3-yl)indo...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132427(5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylid...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149875(CHEMBL361022 | {(R)-4-[5-Chloro-2-(4-methoxy-pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149873(CHEMBL182162 | {(2R,5S)-4-[2-(4-Methoxy-phenylsulf...)
Affinity DataIC50:  160nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132422(5-(Pyridine-3-carbonyl)-3-[1-(1H-pyrrol-2-yl)-meth...)
Affinity DataIC50:  168nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132428(5-(Hydroxy-thiophen-2-yl-methyl)-3-[1-(1H-pyrrol-2...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132417(3-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-5-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132423(2-Oxo-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2,3-...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM17032((3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihyd...)
Affinity DataIC50:  213nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132419(5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylid...)
Affinity DataIC50:  235nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132424(3-[2-Oxo-2-(1H-pyrrol-2-yl)-eth-(Z)-ylidene]-5-(th...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149865(CHEMBL181805 | {4-[5-Chloro-2-(4-methoxy-phenylsul...)
Affinity DataIC50:  290nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149856(CHEMBL360052 | {Methyl-[(R)-3-phenyl-3-(4-trifluor...)
Affinity DataIC50:  320nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132418(5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylid...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149866(CHEMBL181643 | {4-[2-(4-Chloro-phenylsulfanyl)-phe...)
Affinity DataIC50:  360nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149862(CHEMBL182521 | [2,5-Dimethyl-4-(2-p-tolylsulfanyl-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149859(CHEMBL182666 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  580nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132426(CHEMBL104062 | N-{4-[2-Oxo-5-(thiophene-2-carbonyl...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50065287(5-Nitro-3-(1H-pyrrol-2-ylmethylene)-1,3-dihydro-in...)
Affinity DataIC50:  710nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132429(CHEMBL104409 | N-{2-Oxo-3-[1-(1H-pyrrol-2-yl)-meth...)
Affinity DataIC50:  870nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM17015((3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149872(CHEMBL182015 | {4-[2-(Biphenyl-4-ylsulfanyl)-pheny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149868(CHEMBL183030 | {(S)-4-[5-Chloro-2-(4-methoxy-pheny...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149853(CHEMBL181596 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149860(CHEMBL360501 | {4-[2-(4-Methoxy-phenylsulfanyl)-5-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149877(CHEMBL365268 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149876(CHEMBL184785 | {4-[5-Chloro-2-(4-methoxy-phenylsul...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149861(CHEMBL182949 | {4-[2-(4-Fluoro-phenylsulfanyl)-phe...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132431(3-[1-Phenyl-meth-(Z)-ylidene]-5-(thiophene-2-carbo...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149874(CHEMBL363928 | [2,5-Dimethyl-4-(2-phenylsulfanyl-p...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149864(CHEMBL181698 | {4-[2-(4-Hydroxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149863(CHEMBL183508 | {4-[5-Methoxy-2-(4-methoxy-phenylsu...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132425(3-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-5-(thioph...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132430(3-[1-(4-Methanesulfonyl-phenyl)-meth-(Z)-ylidene]-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149854(CHEMBL180202 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149858(CHEMBL184996 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149870(CHEMBL360768 | {(2R,5R)-4-[2-(4-Methoxy-phenylsulf...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149869(CHEMBL182917 | {(2S,5S)-4-[2-(4-Methoxy-phenylsulf...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149857(CHEMBL181745 | {4-[2-(4-Acetylamino-phenylsulfanyl...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149867(CHEMBL182618 | {4-[5-Methoxy-2-(4-methoxy-phenylsu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149855(CHEMBL182916 | {(2S,5R)-4-[2-(4-Methoxy-phenylsulf...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed