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TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467472(CHEMBL4281766)
Affinity DataEC50:  63nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467474(CHEMBL4289471)
Affinity DataEC50:  55nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467473(CHEMBL4292389)
Affinity DataEC50:  191nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467477(CHEMBL4277243)
Affinity DataEC50:  58nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467484(CHEMBL4281590)
Affinity DataEC50:  725nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467490(CHEMBL4278136)
Affinity DataEC50:  71nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467488(CHEMBL4286052)
Affinity DataEC50:  30nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467491(CHEMBL4289291)
Affinity DataEC50:  225nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467479(CHEMBL4281081)
Affinity DataEC50:  103nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataEC50:  78nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50537682(Mogrol)
Affinity DataEC50:  3.00E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537683(CHEMBL4635995)
Affinity DataEC50:  7.40E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537684(CHEMBL4640795)
Affinity DataEC50:  5.00E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537685(CHEMBL4637165)
Affinity DataEC50:  150nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537686(CHEMBL4637006)
Affinity DataEC50:  140nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537687(CHEMBL4643614)
Affinity DataEC50:  1.40E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537688(CHEMBL4636688)
Affinity DataEC50:  4.10E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537689(CHEMBL4648636)
Affinity DataEC50:  3.50E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537690(CHEMBL4639889)
Affinity DataEC50:  500nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537691(CHEMBL4634166)
Affinity DataEC50:  1.40E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537692(CHEMBL4644881)
Affinity DataEC50:  4.70E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537693(CHEMBL4648110)
Affinity DataEC50:  1.50E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537694(CHEMBL4638899)
Affinity DataEC50:  1.70E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537695(CHEMBL4641632)
Affinity DataEC50:  700nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537696(CHEMBL4639939)
Affinity DataEC50:  600nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537697(CHEMBL4648563)
Affinity DataEC50:  200nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537698(CHEMBL4641375)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537699(CHEMBL4644411)
Affinity DataEC50:  1.70E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537700(CHEMBL4640680)
Affinity DataEC50:  500nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537701(CHEMBL4646560)
Affinity DataEC50:  1.60E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537702(CHEMBL4643591)
Affinity DataEC50:  700nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50537703(CHEMBL4641544)
Affinity DataEC50:  500nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM18137(adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4...)
Affinity DataEC50:  1.40E+3nMAssay Description:Allosteric activation of AMPK alpha2/beta1/gamma1 in human HepG2 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50: <0.100nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566265(CHEMBL4861898)
Affinity DataEC50:  2.91E+4nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566266(CHEMBL4879248)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566267(CHEMBL4846094)
Affinity DataEC50:  2.60E+4nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566268(CHEMBL4876271)
Affinity DataEC50:  3.28E+3nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566269(CHEMBL4851337)
Affinity DataEC50:  1.54E+3nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566270(CHEMBL4876319)
Affinity DataEC50:  240nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566271(CHEMBL4871805)
Affinity DataEC50:  2.55E+3nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566272(CHEMBL4860935)
Affinity DataEC50:  1.02E+3nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566273(CHEMBL4875106)
Affinity DataEC50:  330nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566274(CHEMBL4861282)
Affinity DataEC50:  790nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566275(CHEMBL4860982)
Affinity DataEC50:  2.66E+3nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566276(CHEMBL4871204)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566265(CHEMBL4861898)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566266(CHEMBL4879248)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50566267(CHEMBL4846094)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
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