Report error Found 237 with Last Name = 'xue' and Initial = 'lp'
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta 2 strain assessed as binding constant by SPR biosensor ass...More data for this Ligand-Target Pair
Affinity DataKd: 243nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3K4me peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 0.400nMAssay Description:Inhibition of EED (unknown origin) assessed dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Inhibition of EED (unknown origin) assessed dissociation constantMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant GCN2 using eIF2alpha as substrateMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate pr...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant LSD1 (158 to end residues) expressed in Escherichia coli using H3K4me2 peptide substrate preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant GCN2 by P-ATP kinase assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues) expressed in Escherichia coli BL21 (DE3) using ART(mK)QTARKSTGGKAPRKQLAGGK-...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of LSD1 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using monomethylated H3-K4 peptide as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red re...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) by fluorescence plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Inhibition of LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red re...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged full length human LSD1 expressed in Escherichia coli BL21 RIPL Codon Plus (DE3) using ARTK(me2)QTARKSTGGKAPRKQLA as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
Affinity DataIC50: 412nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 450nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of MAO-A (unknown origin) measured after 60 mins by luciferin-based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 526nMAssay Description:Inhibition of MAO-A (unknown origin) preincubated for 20 mins using 5-hydroxytryptamine as substrate followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 553nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
