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LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.72E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504989(CHEMBL4551092)
Affinity DataEC50:  173nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504990(CHEMBL4570987)
Affinity DataEC50:  52nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.52E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  2.66E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50: >2.00E+4nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  1.97E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.01E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.13E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504989(CHEMBL4551092)
Affinity DataEC50:  580nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504994(CHEMBL4553881)
Affinity DataEC50:  132nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504995(CHEMBL4547279)
Affinity DataEC50:  213nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504996(CHEMBL4581904)
Affinity DataEC50:  346nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504997(CHEMBL4463048)
Affinity DataEC50:  35nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504998(CHEMBL4588847)
Affinity DataEC50:  105nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.32E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504999(CHEMBL4453629)
Affinity DataEC50:  247nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.11E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.13E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50505000(CHEMBL4517461)
Affinity DataEC50:  137nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50505001(CHEMBL4461428)
Affinity DataEC50:  48nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50505002(CHEMBL4533405)
Affinity DataEC50:  150nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504989(CHEMBL4551092)
Affinity DataEC50:  820nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50505003(CHEMBL4475985)
Affinity DataEC50:  66nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50505004(CHEMBL4546985)
Affinity DataEC50:  222nMAssay Description:Corrector activity at forskolin-stimulated CFTR F508del mutant in human NHBE cells after 18 to 24 hrs in presence of GLPG1873 by voltage-clamp based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.72E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  2.61E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.52E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  1.94E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.01E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  241nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592362(CHEMBL5181801)
Affinity DataEC50:  188nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592363(CHEMBL5173841)
Affinity DataEC50:  113nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592364(CHEMBL5204350)
Affinity DataEC50:  136nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592365(CHEMBL5187015)
Affinity DataEC50:  190nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592366(CHEMBL5190632)
Affinity DataEC50:  107nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592367(CHEMBL5172188)
Affinity DataEC50:  210nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592368(CHEMBL5177312)
Affinity DataEC50:  184nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592369(CHEMBL5178099)
Affinity DataEC50:  321nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592370(CHEMBL5180378)
Affinity DataEC50:  159nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592371(CHEMBL5203914)
Affinity DataEC50:  41nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592372(CHEMBL5202497)
Affinity DataEC50:  142nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50592373(CHEMBL5180031)
Affinity DataEC50:  22nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192791(2-(5-bromo-pyridin-2-yloxy)-N-((1R,2S,5R,7S)-5-car...)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192792(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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