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TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222186(6-(Dimethylamino)-3-(4'-nitrophenyl)-2,3-dihyd...)
Affinity DataIC50: 110nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222179(6-(Dimethylamino)-3-phenyl-2,3-dihydronaphtho[1,8-...)
Affinity DataIC50: 190nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222188(6-(Dimethylamino)-3-(4'-hydroxy-3'-methoxy...)
Affinity DataIC50: 200nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 270nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222185(6-(Dimethylamino)-3-(3',5'-dichloro-2-hydr...)
Affinity DataIC50: 270nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222190(6-(Dimethylamino)-3-(3'-bromo-4'-methoxyph...)
Affinity DataIC50: 300nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222187(6-(Dimethylamino)-3-(2'-methoxyphenyl)-2,3-dih...)
Affinity DataIC50: 310nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
University of Karachi

LigandPNGBDBM222185(6-(Dimethylamino)-3-(3',5'-dichloro-2-hydr...)
Affinity DataIC50: 380nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222180(6-(Dimethylamino)-3-(4'-dichlorophenyl)-2,3-di...)
Affinity DataIC50: 420nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222191(6-(Dimethylamino)-3-(5'-bromo-2'-hydroxy-3...)
Affinity DataIC50: 440nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222181(6-(Dimethylamino)-3-(4'-methylphenyl)-2,3-dihy...)
Affinity DataIC50: 460nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222182(6-(Dimethylamino)-3-(4'-hydroxyphenyl)-2,3-dih...)
Affinity DataIC50: 500nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222192(6-(Dimethylamino)-3-(2',3',4'-trimetho...)
Affinity DataIC50: 510nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222191(6-(Dimethylamino)-3-(5'-bromo-2'-hydroxy-3...)
Affinity DataIC50: 680nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50028013(CHEMBL3360798)
Affinity DataIC50: 900nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
University of Karachi

LigandPNGBDBM222179(6-(Dimethylamino)-3-phenyl-2,3-dihydronaphtho[1,8-...)
Affinity DataIC50: 1.12E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222192(6-(Dimethylamino)-3-(2',3',4'-trimetho...)
Affinity DataIC50: 1.19E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222184(6-(Dimethylamino)-3-(3'-nitrophenyl)-2,3-dihyd...)
Affinity DataIC50: 1.45E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 1.69E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
LigandPNGBDBM50028010(CHEBI:10127 | AD-810 | CI-912 | PD-110843 | Zonegr...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222190(6-(Dimethylamino)-3-(3'-bromo-4'-methoxyph...)
Affinity DataIC50: 3.48E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222183(6-(Dimethylamino)-3-(4'-thiomethylphenyl)-2,3-...)
Affinity DataIC50: 6.63E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM50241179(6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole...)
Affinity DataIC50: 1.92E+4nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM18073(L-[2,3,4,5,6-3H]phenylalanine | (2S)-2-amino-3-phe...)
Affinity DataIC50: 8.02E+4nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
LigandPNGBDBM50028011(CHEMBL3360810)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50028012(CHEMBL3360801)
Affinity DataIC50: 4.42E+5nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed