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TargetEpidermal growth factor receptor [L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76963(US9694011, Example 1 (Compound 17))
Affinity DataKd:  54nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76973(US9694011, Example 2 (Compound 18))
Affinity DataKd:  6.30nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76963(US9694011, Example 1 (Compound 17))
Affinity DataKd:  270nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76973(US9694011, Example 2 (Compound 18))
Affinity DataKd:  9.30nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76963(US9694011, Example 1 (Compound 17))
Affinity DataKd: <10nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM76973(US9694011, Example 2 (Compound 18))
Affinity DataKd: <10nMT: 2°CAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataKd:  1.40nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  0.540nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  0.0370nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313223(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)-2-methoxy-anil...)
Affinity DataKd:  0.280nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataKd:  46nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataKd:  12nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  84nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  26nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  15nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  4nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEphrin type-A receptor 4 [29-209](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223300(EphA4-LBC inhibitor, Compound 22)
Affinity DataKd:  1.20E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223305(123C2)
Affinity DataKd:  1.10E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223308(123C5)
Affinity DataKd:  2.20E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223310(123C7)
Affinity DataKd:  540nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  420nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 3 [29-207](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  4.55E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,I59G](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  3.66E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,I59A](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  9.09E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,I67A](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  780nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,I159A](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  290nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,M60A](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  350nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,M164A](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  62nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4 [29-209,D61G,E62G](Human)
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  340nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466941(3-((2,2-difluorocyclopropyl)methyl)- 7-(m-tolyl)-[...)
Affinity DataEC50:  143nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466942(3-((2,2-Difluorocyclopropyl)methyl)- 7-(3-fluoroph...)
Affinity DataEC50:  704nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466943(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoroph...)
Affinity DataEC50:  381nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466944(2-(4-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]...)
Affinity DataEC50:  226nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466945(3-((2,2-difluorocyclopropyl)methyl)- 7-(3-fluoro-4...)
Affinity DataEC50:  849nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466946(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-2...)
Affinity DataEC50:  781nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466947(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3...)
Affinity DataEC50:  868nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466948(Methyl 4-(3-((2,2-difluorocyclopropyl) methyl)-[1,...)
Affinity DataEC50:  541nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466949(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataEC50:  368nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466950(3-((2,2-difluorocyclopropyl)methyl)- 7-(2,3-benzod...)
Affinity DataEC50:  825nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466951(8-(3-((2,2-difluorocyclopropyl) methyl)-[1,2,4]tri...)
Affinity DataEC50:  612nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466952(7-(Benzo[d][1,3]dioxol-5-yl)- 3-((2,2-difluorocycl...)
Affinity DataEC50:  108nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466953(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(m...)
Affinity DataEC50:  130nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466954(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataEC50:  190nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466955(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(4...)
Affinity DataEC50:  856nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466956(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataEC50:  118nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466957(Methyl 4-(8-Chloro-3- ((2,2-difluorocyclopropyl) m...)
Affinity DataEC50:  87.9nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466958(Methyl 3-Chloro-4-(8-chloro- 3-((2,2-difluorocyclo...)
Affinity DataEC50:  230nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466959(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(2...)
Affinity DataEC50:  215nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466960(7-(Benzo[d][1,3]dioxol-5-yl)-8-chloro- 3-((2,2-dif...)
Affinity DataEC50:  62.3nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466961(US10800776, Example D35)
Affinity DataEC50:  970nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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