Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 7305 with Last Name = 'zhang' and Initial = 'b'
Target5-hydroxytryptamine receptor 4(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210557(CHEMBL242756 | MCL-147)
Affinity DataKi:  0.0490nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAspartate--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50339907(((S)-2-amino-3-carboxypropanoyl)(((2R,3S,4R,5R)-5-...)
Affinity DataKi:  0.0520nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Aspartyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataKi:  0.0620nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343625((-)-17-N-Cyclobutylmethyl)morphinan-3-yl-(-)-14-hy...)
Affinity DataKi:  0.0730nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.0790nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.0790nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.0790nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135797(CHEMBL146756 | di[17-cyclobutylmethyl-(1R,9R,10R)-...)
Affinity DataKi:  0.0800nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343625((-)-17-N-Cyclobutylmethyl)morphinan-3-yl-(-)-14-hy...)
Affinity DataKi:  0.0890nMAssay Description:Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0900nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataKi:  0.100nMAssay Description:Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in rat brain membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human JAK2 (828-1132) expressed in baculovirus-infected Sf9 cells using EQEDEPEGDYFEWLE as substrate after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532777(CHEMBL4470925)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in rat brain membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532777(CHEMBL4470925)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50240437((-)-17-(cyclobutylmethyl)morphinan-3,14-diol | (-)...)
Affinity DataKi:  0.120nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50300380((1R,10R)-17-(cyclobutylmethyl)-17-azatetracyclo[7....)
Affinity DataKi:  0.130nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50458119(Leusa)
Affinity DataKi:  0.139nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343629((-)-14-Methoxybutorphanol | CHEMBL1774946)
Affinity DataKi:  0.140nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343627(Benzyl-(-)-14-methoxy-butorphanol-3-yl-decanedioat...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50386664(CHEMBL2048772)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50386678(CHEMBL2048766)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137997(3-Amino-N-cyclopropylmethylmorphinan | 3-aminocycl...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50339906(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Seryl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135797(CHEMBL146756 | di[17-cyclobutylmethyl-(1R,9R,10R)-...)
Affinity DataKi:  0.200nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343629((-)-14-Methoxybutorphanol | CHEMBL1774946)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50067499((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to mouse CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human JAK1 (837-1142) expressed in baculovirus-infected Sf9 cells using EQEDEPEGDYFEWLE as substrate after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCannabinoid receptor 2(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50532778(CHEMBL4465566 | US10882838, Example 3.6)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50067499((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to mouse CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50240437((-)-17-(cyclobutylmethyl)morphinan-3,14-diol | (-)...)
Affinity DataKi:  0.220nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.230nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  0.230nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343627(Benzyl-(-)-14-methoxy-butorphanol-3-yl-decanedioat...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 7305 total ) | Next | Last >>
Jump to: