Report error Found 287 with Last Name = 'zhang' and Initial = 'jw'
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of IFNgamma-stimulated IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Time dependent inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells measured after 60 mins by FRET ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Time dependent inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells measured after 30 mins by FRET ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Affinity DataIC50: 51.3nMT: 2°CAssay Description:D2 receptor/G protein α16a co-transfected HEK293 cells (from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences) were seeded ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Affinity DataIC50: 57.3nMT: 2°CAssay Description:D2 receptor/G protein α16a co-transfected HEK293 cells (from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences) were seeded ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Time dependent inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells measured after 15 mins by FRET ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Affinity DataIC50: 87.7nMT: 2°CAssay Description:D2 receptor/G protein α16a co-transfected HEK293 cells (from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences) were seeded ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Affinity DataIC50: 116nMT: 2°CAssay Description:D2 receptor/G protein α16a co-transfected HEK293 cells (from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences) were seeded ...More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Time dependent inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells measured after 5 mins by FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) Rosetta competent cells using DabcylKNSTLQSGLRKE-Edan as fluorescence ...More data for this Ligand-Target Pair







3D Structure (crystal)





























