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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557256(US11352354, Example V-c-1)
Affinity DataKd:  1.30E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557257(US11352354, Example V-c-2)
Affinity DataKd:  2.00E+6nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557258(US11352354, Example V-c-10)
Affinity DataKd:  3.50E+6nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557259(US11352354, Example V-c-11)
Affinity DataKd:  7.00E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557260(US11352354, Example V-c-12)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557261(US11352354, Example V-c-13)
Affinity DataKd:  1.60E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557262(US11352354, Example V-c-14)
Affinity DataKd:  2.00E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557263(US11352354, Example V-c-15)
Affinity DataKd:  1.40E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557264(US11352354, Example V-c-16)
Affinity DataKd:  1.10E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557266(US11352354, Example V-c-18)
Affinity DataKd:  6.40E+3nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557267(US11352354, Example V-c-19)
Affinity DataKd:  1.60E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557267(US11352354, Example V-c-19)
Affinity DataKd:  1.50E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557268(US11352354, Example V-c-20)
Affinity DataKd:  1.00E+6nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557269(US11352354, Example V-c-21)
Affinity DataKd:  9.10E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557270(US11352354, Example V-c-22)
Affinity DataKd:  2.10E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557271(US11352354, Example V-c-23)
Affinity DataKd:  3.30E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557272(US11352354, Example V-c-24)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557273(US11352354, Example V-c-38)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557274(US11352354, Example V-c-39)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557275(US11352354, Example V-c-4)
Affinity DataKd:  3.30E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557276(US11352354, Example V-c-40)
Affinity DataKd:  3.80E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557277(US11352354, Example V-c-41)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557278(US11352354, Example V-c-42)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557279(US11352354, Example V-c-43)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557280(US11352354, Example V-c-51)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557281(US11352354, Example V-c-52)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557282(US11352354, Example V-c-53)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557283(US11352354, Example V-c-6)
Affinity DataKd:  1.60E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557284(US11352354, Example V-c-61)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557285(US11352354, Example V-c-62)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557286(US11352354, Example V-c-63)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557287(US11352354, Example V-c-8)
Affinity DataKd:  1.30E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557288(US11352354, Example V-c-9)
Affinity DataKd:  2.90E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
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TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataKd:  5.20E+3nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataKd:  5.10E+3nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616156(US20230271966, Compound 12 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd:  280nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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PDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616156(US20230271966, Compound 12 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616157(US20230271966, Compound 13 | 2-(2,6-dioxopiperidin...)
Affinity DataKd:  1.90E+3nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616157(US20230271966, Compound 13 | 2-(2,6-dioxopiperidin...)
Affinity DataKd:  540nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616158(US20230271966, Compound 22 | (R)-4-hydroxy-2-(3-me...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616158(US20230271966, Compound 22 | (R)-4-hydroxy-2-(3-me...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616159(US20230271966, Compound 30 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd:  360nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616159(US20230271966, Compound 30 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633517(US11807606, Compound 1)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633518(US11807606, Compound 2)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633519(US11807606, Compound 3)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633520(US11807606, Compound 4)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633521(US11807606, Compound 5)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDDB1- and CUL4-associated factor 15(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM633522(US11807606, Compound 6)
Affinity DataEC50:  5.50E+3nMAssay Description:Increasing concentrations of compounds were added to pre-mixed biotinylated DCAF15 at 200 nM, Bodipy-FL-labelled RRM2 domain in RBM39 at 200 nM, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

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