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TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194731(US9670211, 1-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194732(US9670211, 1-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194733(US9670211, 2-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194734(US9670211, 2-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194735(US9670211, 2-3 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194736(US9670211, 2-4 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194737(US9670211, 2-5 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194738(US9670211, 2-6 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194739(US9670211, 2-7 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194740(US9670211, 2-8 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194741(US9670211, 2-9 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194742(US9670211, 2-10 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194743(US9670211, 2-11 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194744(US9670211, 2-12 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194745(US9670211, 2-13 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194746(US9670211, 2-14 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194747(US9670211, 2-15 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194748(US9670211, 2-16 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194749(US9670211, 2-17 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194750(US9670211, 3-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194751(US9670211, 3-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194752(US9670211, 3-3 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194753(US9670211, 4-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194868(US9670211, 4-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194869(US9670211, 4-3 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194874(US9670211, 5 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194882(US9670211, 6 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194950(US9670211, 7-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM194975(US9670211, 7-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195000(US9670211, 8-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195001(US9670211, 8-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195002(US9670211, 9-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195003(US9670211, 9-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195019(US9670211, 10-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195020(US9670211, 10-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195021(US9670211, 11 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195044(US9670211, 12 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195060(US9670211, 13 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195068(US9670211, 14-1 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195072(US9670211, 14-2 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195075(US9670211, 15 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195076(US9670211, 16 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195077(US9670211, 17 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195078(US9670211, 18 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMajor surface glycoprotein G(Human respiratory syncytial virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM195079(US9670211, 19 )
Affinity DataAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...)
Affinity DataEC50:  800nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM262091(US9708325, S-1 | US11242345, Example S-1)
Affinity DataEC50:  370nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50274596(6-amino-9-benzyl-N-(2-methoxyethyl)-8-oxo-8,9-dihy...)
Affinity DataEC50:  270nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM262093(US9708325, P-5 | US11242345, Example P-5)
Affinity DataEC50:  3.14E+3nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM262094(6-Amino-9-benzyl-2-(methylsulfonimidoyl)-7H-purin-...)
Affinity DataEC50:  300nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

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