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TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332027(US10196346, Example 1 | (E)-N'-(3-methoxy-2- hydro...)
Affinity DataEC50:  2.29E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332028(US10196346, Example 2 | (E)-N'-(3,5-di-tert-butyl-...)
Affinity DataEC50:  1.78E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332029(US10196346, Example 3 | (E)-N'-(3-ethoxy-2- hydrox...)
Affinity DataEC50:  2.11E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332030(US10196346, Example 4 | (E)-N'-[(2- hydroxynaphtha...)
Affinity DataEC50:  830nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332031(US10196346, Example 5 | (E)-N'-(4-N,N- diethylamin...)
Affinity DataEC50:  780nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332032(US10196346, Example 8 | (E)-N'-(3,5-di-tert-butyl-...)
Affinity DataEC50:  5.23E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332033(US10196346, Example 10 | (E)-N'-(4-N,N- diethylami...)
Affinity DataEC50:  600nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332034(US10196346, Example 11 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  170nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332035(US10196346, Example 13 | (E)-N'-[(3-ethoxy-2- hydr...)
Affinity DataEC50:  800nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332036(US10196346, Example 14 | (E)-N'-[(2- hydroxynaphth...)
Affinity DataEC50:  1.02E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332037(US10196346, Example 15 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  1.12E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332038(US10196346, Example 17 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  560nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332039(US10196346, Example 18 | (E)-N'-(3-bromo-6- hydrox...)
Affinity DataEC50:  2.28E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332040(US10196346, Example 22 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  2.77E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332041(US10196346, Example 23 | (E)-N'-(4-N,N- diethylami...)
Affinity DataEC50:  760nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332042(US10196346, Example 24 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  820nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332043(US10196346, Example 25 | (E)-N'-(3-bromo-6- hydrox...)
Affinity DataEC50:  7.19E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332044(US10196346, Example 26 | (E)-N'-[(2- hydroxynaphth...)
Affinity DataEC50:  980nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332045(US10196346, Example 27 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  7.75E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332046(US10196346, Example 28 | (E)-N'-(3-methoxy-2- hydr...)
Affinity DataEC50:  8.42E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332047(US10196346, Example 29 | (E)-N'-(3-ethoxy-2- hydro...)
Affinity DataEC50:  2.77E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332048(US10196346, Example 30 | (E)-N'-(4-N,N-diethylamin...)
Affinity DataEC50:  530nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332049(US10196346, Example 31 | (E)-N'-(3-methoxy-2- hydr...)
Affinity DataEC50:  2.76E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332050(US10196346, Example 32 | (E)-N'-(3-ethoxy-2- hydro...)
Affinity DataEC50:  1.86E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM332051(US10196346, Example 33 | (E)-N'-(4-N,N-diethylamin...)
Affinity DataEC50:  130nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandPNGBDBM50042874(2,2'-bipyridine | 2,2'-Bipyridin | 2,2'-bipyridyl ...)
Affinity DataEC50:  4.14E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Academy of Military Medical Sciences

US Patent
LigandPNGBDBM50548985(CHEMBL4792711 | US20230303494, Compound 4)
Affinity DataKd:  1.81nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Academy of Military Medical Sciences

US Patent
LigandPNGBDBM50548983(CHEMBL4795176 | US20230303494, Compound 5)
Affinity DataKd:  0.0160nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Academy of Military Medical Sciences

US Patent
LigandPNGBDBM50548982(CHEMBL4783983 | US20230303494, Compound 10)
Affinity DataKd:  0.296nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Academy of Military Medical Sciences

US Patent
LigandPNGBDBM50548981(CHEMBL4790354 | US20230303494, Compound 11)
Affinity DataKd:  0.515nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Academy of Military Medical Sciences

US Patent
LigandPNGBDBM620574(US20230303494, Compound 37)
Affinity DataKd:  67.5nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50459313(CHEMBL4206744)
Affinity DataEC50:  3.63E+3nMAssay Description:Inhibition of HIV1 envelope glycoprotein-mediated cell-cell fusion between HL2/3 cells stably expressing HIV Gag, Env, Tat, Rev and Nef proteins and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEnvelope glycoprotein(ZEBOV)
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50459313(CHEMBL4206744)
Affinity DataEC50:  1.02E+3nMAssay Description:Inhibition of Ebola virus Sudan envelope glycoprotein-mediated cell entry in human HuH7 cells treated with 30 mins pre-treated pseudovirus/compopund ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513528(CHEMBL4440214)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513541(CHEMBL4533415)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513553(CHEMBL4584669)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513538(CHEMBL4454157)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513552(CHEMBL4458638)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513554(CHEMBL4438487)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513547(CHEMBL4471366)
Affinity DataEC50:  0.640nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513545(CHEMBL4576915)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513551(CHEMBL4447310)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513550(CHEMBL4564192)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513537(CHEMBL4468448)
Affinity DataEC50:  8.5nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513531(CHEMBL4435740)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargettRNA (guanine-N(1)-)-methyltransferase(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Singapore-Mit Alliance For Research and Technology

Curated by ChEMBL
LigandPNGBDBM50519348(CHEMBL4517402)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to full length Staphylococcus aureus tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surface pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargettRNA (guanine-N(1)-)-methyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Singapore-Mit Alliance For Research and Technology

Curated by ChEMBL
LigandPNGBDBM50519349(CHEMBL2431997)
Affinity DataKd:  1.04E+4nMAssay Description:Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargettRNA (guanine-N(1)-)-methyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Singapore-Mit Alliance For Research and Technology

Curated by ChEMBL
LigandPNGBDBM50519348(CHEMBL4517402)
Affinity DataKd:  190nMAssay Description:Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargettRNA (guanine-N(1)-)-methyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Singapore-Mit Alliance For Research and Technology

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataKd:  1.01E+4nMAssay Description:Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargettRNA (guanine-N(1)-)-methyltransferase(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Singapore-Mit Alliance For Research and Technology

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to full length Staphylococcus aureus tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surface pla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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