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TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)
Affinity DataEC50:  860nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448297(MI-12)
Affinity DataEC50:  530nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448299(MI-14)
Affinity DataEC50:  660nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448314(MI-28)
Affinity DataEC50:  670nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448316(MI-30)
Affinity DataEC50:  540nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448317(MI-31)
Affinity DataEC50:  830nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)
Affinity DataEC50:  1.20nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448297(MI-12)
Affinity DataEC50:  7.30nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448299(MI-14)
Affinity DataEC50:  0.300nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448314(MI-28)
Affinity DataEC50:  2.20nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448316(MI-30)
Affinity DataEC50:  1.10nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448317(MI-31)
Affinity DataEC50:  0.400nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)
Affinity DataEC50:  35nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448297(MI-12)
Affinity DataEC50:  97nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448299(MI-14)
Affinity DataEC50:  85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448230(11b | MI-02)
Affinity DataEC50:  75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448314(MI-28)
Affinity DataEC50:  42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448316(MI-30)
Affinity DataEC50:  31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448317(MI-31)
Affinity DataEC50:  62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448319(GC376 | GC-376)
Affinity DataEC50:  175nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50:  2.54E+3nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491484(CHEMBL2382125)
Affinity DataEC50:  4.28E+3nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491485(CHEMBL2382124)
Affinity DataEC50:  1.77E+4nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491486(CHEMBL2382123)
Affinity DataEC50:  2.76E+3nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491487(CHEMBL2382127)
Affinity DataEC50:  2.53E+4nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50428380(E214 | Ethyl Parahydroxybenzoate | ETHYLPARABEN)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4374(p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...)
Affinity DataEC50:  1.61E+4nMAssay Description:Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50428380(E214 | Ethyl Parahydroxybenzoate | ETHYLPARABEN)
Affinity DataEC50:  3.82E+4nMAssay Description:Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491488(CHEMBL2382126)
Affinity DataEC50:  4.84E+4nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491489(CHEMBL2382121)
Affinity DataEC50:  3.38E+4nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491486(CHEMBL2382123)
Affinity DataEC50:  8.32E+3nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491484(CHEMBL2382125)
Affinity DataEC50:  8.17E+3nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50:  1.66E+3nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491488(CHEMBL2382126)
Affinity DataEC50:  4.92E+4nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491485(CHEMBL2382124)
Affinity DataEC50:  1.26E+4nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491490(CHEMBL2382120)
Affinity DataEC50:  7.24E+4nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491491(CHEMBL2382122)
Affinity DataEC50:  2.55E+3nMAssay Description:Antagonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4374(p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...)
Affinity DataEC50:  4.89E+3nMAssay Description:Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50491491(CHEMBL2382122)
Affinity DataEC50:  4.68E+3nMAssay Description:Antagonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd:  86nMAssay Description:Binding affinity to wild type human partial length DDR2 (V555 to E855 residues) expressed in mammalian expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length CAMK1D (M1 to K299 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length CLK4 (R135 to K481 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd:  7.80nMAssay Description:Binding affinity to wild type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system after 1 hr by Kinomescan meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50519158(CHEMBL4445812)
Affinity DataKd:  7.11E+3nMAssay Description:Binding affinity to human partial length PIK3CA Q546K mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519158(CHEMBL4445812)
Affinity DataKd:  7.11E+3nMAssay Description:Binding affinity to wild-type human partial length PIK3C2G (M1 to I1446 residues) expressed in mammalian expression system measured after 1 hr by kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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