Affinity DataEC50: 0.200nMAssay Description:Effective concentration required for stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.320nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.398nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.398nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.501nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Positive allosteric modulator activity at human muscarinic receptor subtype 1 expressed in CHO-K1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.760nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.794nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium level by FL...More data for this Ligand-Target Pair
Affinity DataEC50: 0.850nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.990nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium level by FL...More data for this Ligand-Target Pair
Affinity DataEC50: 1.04nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.06nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:In vitro functional agonism against M1 muscarinic receptor (PI)More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Positive allosteric modulator activity at human muscarinic receptor subtype 1 expressed in CHO-K1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human m1 muscarinic acetylcholine receptor expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.71nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human muscarinic M1 acetylcholine receptor expressed CHO cells assessed as intracellular calcium mobilization after 1 hr by Fluo-...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.More data for this Ligand-Target Pair
Affinity DataEC50: 2.51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 3.16nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.16nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.16nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium level by FL...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
