Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 1150 for UniProtKB: P29466
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289397(3-[(1-{3-Methyl-2-[(naphthalene-2-carbonyl)-amino]...)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289410(CHEMBL26544 | Peptidic phenyl ketoether analogue)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289398(CHEMBL553107 | Peptidic phenyl ketoether analogue)
Affinity DataKi:  0.200nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068972((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068972((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  0.370nMAssay Description:The binding affinity against IL-1 beta converting enzymeChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324937((R)-2-((S)-2-isopropyl-4-(2-(naphthalen-1-yl)ethyl...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50199769((S)-3-((1S,9S)-9-(isoquinoline-1-carboxamido)-6,10...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM10355((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM10355((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)
Affinity DataKi:  0.760nMAssay Description:The compound was tested for inhibition of IL-1 beta converting enzyme in whole human blood.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068954((S)-5-Butylamino-3-(2-{3-[(naphthalene-2-carbonyl)...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50602641(VRT 043198 | Vrt 043198)
Affinity DataKi:  0.800nMAssay Description:Inhibition of caspase 1 (unknown origin)More data for this Ligand-Target Pair
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068949((S)-5-Hexylamino-3-(2-{3-[(naphthalene-2-carbonyl)...)
Affinity DataKi:  0.850nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324953((R)-2-((S)-4-(2-(1,2-dimethyl-1H-indol-3-yl)ethyla...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324938((R)-2-((S)-4-(2-(3-chlorophenylamino)ethylamino)-2...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50325241(CHEMBL1223114)
Affinity DataKi:  1nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50325237((5S,8S,11S)-11-(2-(3,3-diphenylpropanoyloxy)acetyl...)
Affinity DataKi:  1nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50058530((S)-3-{[(1S,9S)-9-(2-Fluoro-benzoylamino)-6,10-dio...)
Affinity DataKi:  1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50058526((S)-3-{[(1S,9S)-9-(4-Carboxymethoxy-benzoylamino)-...)
Affinity DataKi:  1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289405(CHEMBL2371932 | Peptidic phenyl ketoether analogue)
Affinity DataKi:  1.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068950((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324960((R)-2-((S)-2-isopropyl-4-oxo-4-(2-(2,5,6-trimethyl...)
Affinity DataKi:  1.26nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324952((R)-2-((S)-2-isopropyl-4-(2-(2-methyl-1H-indol-3-y...)
Affinity DataKi:  1.29nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084633((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084633((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.30nMAssay Description:The binding affinity against IL-1 beta converting enzymeChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324946((R)-2-((S)-2-isopropyl-4-oxo-4-(2-(quinolin-4-yl)e...)
Affinity DataKi:  1.31nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289402((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289412((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.5nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289393((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068945((S)-5-(Hexyl-methyl-amino)-3-(2-{3-[(naphthalene-2...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091577((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324948((R)-2-((S)-2-isopropyl-4-oxo-4-(2-(quinolin-5-yl)e...)
Affinity DataKi:  1.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50325238((5S,8S,11S)-11-(2-(2-benzyl-3-phenylpropanoyloxy)a...)
Affinity DataKi:  2nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50325240(CHEMBL1223113)
Affinity DataKi:  2nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289407((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289388((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2.20nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068953((S)-5-(Butyl-ethyl-amino)-3-(2-{3-[(naphthalene-2-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068951((S)-5-Dihexylamino-3-(2-{3-[(naphthalene-2-carbony...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282978(3-{(S)-2-[(S)-3-Methyl-2-(3-phenyl-propionylamino)...)
Affinity DataKi:  2.70nMAssay Description:Tested for inhibition of cysteine proteinase IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324957((R)-2-((S)-4-(2-(5,6-dimethyl-1H-benzo[d]imidazol-...)
Affinity DataKi:  2.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324947((R)-2-((S)-4-(2-(2-(dimethylamino)quinolin-4-yl)et...)
Affinity DataKi:  3nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50325236((5S,8S,11S)-5-isopropyl-8-methyl-11-(2-(2-(naphtha...)
Affinity DataKi:  3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068962((S)-5-(Butyl-methyl-amino)-3-(2-{3-[(naphthalene-2...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068957((S)-5-Benzylamino-3-(2-{3-[(naphthalene-2-carbonyl...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324959((S)-3-((S)-2-isopropyl-4-oxo-4-(2-(2-(pyridin-3-yl...)
Affinity DataKi:  3.85nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50139702(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50176494((3S)-3-(6-(3-methyl-4-(quinoxalin-2-ylamino)benzam...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50176493((S)-3-((S)-2-((S)-3-methyl-2-(4-(quinoxalin-2-ylam...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50139695(3-((S)-2-{(S)-2-[2-((S)-Acetylamino)-3-(4-hydroxy-...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068967(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50324954((R)-2-((S)-4-(2-(1H-indol-1-yl)ethylamino)-2-isopr...)
Affinity DataKi:  4.03nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1150 total ) | Next | Last >>
Jump to: