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TargetGenome polyprotein [2420-3010,C2735L](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  2.20nM Kon:  0.0000760M-1s-1 Koff:  3.50E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,S2701T](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  3.90nM Kon:  0.000130M-1s-1 Koff:  3.40E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  5.20nM Kon:  0.000100M-1s-1 Koff:  2.00E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,M2833T](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  5.90nM Kon:  0.000150M-1s-1 Koff:  2.60E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,M2842T](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  6.30nM Kon:  0.000150M-1s-1 Koff:  2.50E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,V2913A](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  1.50E+3nM Kon:  0.000840M-1s-1 Koff:  5.50E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,P2914L](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  3.80E+3nM Kon:  0.0220M-1s-1 Koff:  5.90E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,L2811I](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  5.50E+3nM Kon:  0.000970M-1s-1 Koff:  1.80E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010,P2914L](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  6.40E+3nM Kon:  0.0220M-1s-1 Koff:  3.40E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent