Affinity DataKi: 0.00140nMAssay Description:Inhibitory concentration against recombinant human caspase-3 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibitory concentration against recombinant human caspase-3 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of caspase-3 (unknown origin) using Ac-DEVD-AMCA as substrate incubated for 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 0.230nM ΔG°: -55.0kJ/molepH: 7.5 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM IC50: 2.5nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Enzyme activities with or without inhibitors were measured using a fluorescence assay. The formation of the cleavage product AFC was monitored for 90...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of human caspase 3 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 4.40nM IC50: 3.90nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 10.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Enzyme activities with or without inhibitors were measured using a fluorescence assay. The formation of the cleavage product AFC was monitored for 90...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 14.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 15nM IC50: 44nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Evaluated for the dissociation constant for the inhibition of caspase-3More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 16.1nMAssay Description:Enzyme activities with or without inhibitors were measured using a fluorescence assay. The formation of the cleavage product AFC was monitored for 90...More data for this Ligand-Target Pair
Affinity DataKi: 17.9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 19nM IC50: 31nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity against Caspase-3More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 23.5nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of caspase-3 (unknown origin) using Ac-DEVD-AMCA as substrate incubated for 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Compound was tested for its inhibition against Caspase-3More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -42.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -42.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -42.9kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -42.2kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 41.8nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 56.1nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.9kJ/mole IC50: 120nMpH: 7.5 T: 30°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
