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TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341160(3-(anthracen-9-yl)-5-(3-nitrophenyl)-4,5-dihydro-1...)
Affinity DataKi:  0.450nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341161(3-(anthracen-9-yl)-5-(4-methoxyphenyl)-4,5-dihydro...)
Affinity DataKi:  0.600nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087800((5-Benzyloxy-1H-indol-2-ylmethyl)-prop-2-ynyl-amin...)
Affinity DataKi:  0.75nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50304157(3-(2-Thienyl)-2-thiocarbamoyl-2,3,4,5,6,7-hexahydr...)
Affinity DataKi:  0.900nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50304152(3-(2-Furyl)-2-thiocarbamoyl-2,3,4,5,6,7-hexahydro-...)
Affinity DataKi:  0.960nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341154(3-(anthracen-9-yl)-5-(4-chlorophenyl)-4,5-dihydro-...)
Affinity DataKi:  2.10nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341152(3-(anthracen-9-yl)-5-(4-nitrophenyl)-4,5-dihydro-1...)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087809(CHEMBL298006 | Methyl-(1-methyl-1H-indol-2-ylmethy...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341156(3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...)
Affinity DataKi:  3.43nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341155(3-(anthracen-9-yl)-5-p-tolyl-4,5-dihydro-1H-pyrazo...)
Affinity DataKi:  3.80nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087796((5-Methoxy-1-methyl-1H-indol-2-ylmethyl)-prop-2-yn...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341158(4-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Affinity DataKi:  4.77nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341157(2-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Affinity DataKi:  5.91nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341153(4-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Affinity DataKi:  6.75nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50341159(2-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Affinity DataKi:  9.91nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataKi:  11nMAssay Description:Non-competitive inhibition of rat liver mitochondrial MAO-B using phenylethylamine as substrate by Line-Weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087807((5-Benzyloxy-1H-indol-2-ylmethyl)-but-2-ynyl-amine...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087794(But-2-ynyl-methyl-(1-methyl-1H-indol-2-ylmethyl)-a...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087801((5-Methoxy-1-methyl-1H-indol-2-ylmethyl)-methyl-pr...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50386547(CHEMBL2048234)
Affinity DataKi:  33.1nMAssay Description:Displacement of [3H]-Ro 16-6491 from MAO-B receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307363((+/-)-2-(4'-Benzyloxyphenyl)thiomorpholin-5-one | ...)
Affinity DataKi:  74nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307362((+/-)-2-(4'-Benzyloxyphenyl)thiomorpholine | CHEMB...)
Affinity DataKi:  130nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50247671(2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]...)
Affinity DataKi:  160nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307364((+/-)-2-(4'-Butoxyphenyl)thiomorpholin-5-one | CHE...)
Affinity DataKi:  160nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataKi:  220nMAssay Description:Competitive inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307367((+/-)-2-(4'-Butoxyphenyl)thiomorpholine | CHEMBL59...)
Affinity DataKi:  270nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087791(But-2-ynyl-(5-methoxy-1-methyl-1H-indol-2-ylmethyl...)
Affinity DataKi:  370nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50305211(3-(2-hydroxyphenyl), 5-(4-hydroxyphenyl)-4, 5-dihy...)
Affinity DataKi:  600nMAssay Description:Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50276775(1-(4-(benzyloxy)phenyl)propan-2-amine | CHEMBL4560...)
Affinity DataKi:  710nMAssay Description:Inhibition of MAOB in rat brain mitochondriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50305210(3,5-bis-(2-hydroxyphenyl)-4, 5-dihydro-1H-pyrazole...)
Affinity DataKi:  780nMAssay Description:Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50087803(1-Methyl-2-[(methyl-prop-2-ynyl-amino)-methyl]-1H-...)
Affinity DataKi:  820nMAssay Description:Inhibitory activity against Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  970nMAssay Description:Reversible inhibition of MAO-B in Wistar rat assessed as inhibition constant followed by using clorgyline as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307366((+/-)-2-(4'-Propoxyphenyl)thiomorpholine | CHEMBL6...)
Affinity DataKi:  980nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM85709(S18616)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50241196((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15613(4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-ch...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15613(4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-ch...)
Affinity DataKi:  1.08E+3nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.12kcal/molepH: 7.4 T: 25°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50304156(3-(2-Furyl)-2-(N-phenyllthiocarbamoyl)-3,3a,4,5,6,...)
Affinity DataKi:  1.23E+3nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  1.35E+3nMAssay Description:Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  1.35E+3nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50265993(CHEMBL451230 | phenyl 4-(4,5-dihydro-1H-imidazol-2...)
Affinity DataKi:  1.38E+3nMAssay Description:Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50247755(2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-y...)
Affinity DataKi:  1.48E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50307368((+/-)-2-(4'-Propoxyphenyl)thiomorpholin-5-one | CH...)
Affinity DataKi:  1.49E+3nMAssay Description:Inhibition of MAOB in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50240366(2-(naphthalen-2-yl)-4,5-dihydro-1H-imidazole | 2-N...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50386544(CHEMBL2048231)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]-Ro 16-6491 from MAO-B receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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