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TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521345(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50:  3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521334(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521421(6-(2,4- dichlorophenyl)- 1-fluoro-5-[6- [(3S)-1-(3...)
Affinity DataIC50:  3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521296(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50:  4nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521416(6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...)
Affinity DataIC50:  4nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521360(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50:  4nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521255(3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...)
Affinity DataIC50:  5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521384(4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...)
Affinity DataIC50:  5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521413(6-(2-fluoro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50:  5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521262(6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [[(3S)-1-(...)
Affinity DataIC50:  5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521270(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521383(4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521295(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521374(4-(2,2- dimethylindolin- 5-yl)-5-[4-[(3S)- 1-(3- f...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521267(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521192(3-(2-fluoro-4- methyl-phenyl)- 4-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  6nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521354(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  7nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)
Affinity DataIC50:  7nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521182(7-(2-fluoro-4- hydroxy- phenyl)-8-[4- [(3S)-1-(3- ...)
Affinity DataIC50:  8nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521341(4-(4-fluoro-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  8nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521336(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  8nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521198(3-(2-chloro-4- fluoro-phenyl)- 4-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521415(6-(2,4- dichlorophenyl)- 5-[6-[(3S)-1-(3- fluoropr...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521382(4-(2-chloro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521344(4-(2-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521428(6-(6-ethoxy-2- fluoro-3- pyridyl)-1- fluoro-5-[6- ...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521340(4-(2-fluoro-4- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521335(4-(2-chloro-4- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  10nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521378(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  11nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521381(4-(2,4- dichlorophenyl)- 5-[(6-[(3S)-1-(3- fluorop...)
Affinity DataIC50:  11nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521195(4-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  11nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521297(4-(2-fluoro-4- methoxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50:  13nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521373(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  13nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521425(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-1- fluo...)
Affinity DataIC50:  14nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521221(3-(2-fluoro-6- methoxy-3- pyridyl)-4-[4- [(3S)-1-(...)
Affinity DataIC50:  14nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521193(3-(4-chloro-3- methyl-phenyl)- 4-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  14nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521377(4-(2,2-dimethyl- 3H-benzofuran- 5-yl)-5-[4-[(3S)- ...)
Affinity DataIC50:  15nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521380(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  15nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521261(6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...)
Affinity DataIC50:  15nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521254(3-(2-fluoro-4- methyl-phenyl)- 4-[6-[(3S)-1-(3- fl...)
Affinity DataIC50:  15nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521194(3-(4-chloro-2- fluoro-phenyl)- 4-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  15nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521343(4-(4-chloro-2- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  16nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521356(4-(4-fluoro-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  16nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521282(9-fluoro-4-(2- fluoro-4-methyl- phenyl)-5-[4- [(3S...)
Affinity DataIC50:  16nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521417(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50:  16nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521362(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  16nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521273(4-(4-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50:  18nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521348(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50:  18nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521297(4-(2-fluoro-4- methoxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50:  19nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM521197(3-(2,4- dichlorophenyl)- 4-[4-[(3S)-1-(3- fluoropr...)
Affinity DataIC50:  19nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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