Compile Data Set for Download or QSAR
maximum 50k data
Found 315 of ic50 for UniProtKB: O60885
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528596(US11192900, Compound 16 | US11192900, Example S-23)
Affinity DataIC50:  6nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528648(US11192900, Compound 616 | US11192900, Compound 70...)
Affinity DataIC50:  11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528647(US11192900, Compound 661 | US11192900, Example S-7...)
Affinity DataIC50:  20nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528646(US11192900, Compound 406 | US11192900, Example S-7...)
Affinity DataIC50:  22nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50:  24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50:  24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528612(US11192900, Compound 29 | US11192900, Example S-36)
Affinity DataIC50:  30nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM528582(US11192900, Compound 2 | US11192900, Example S-9)
Affinity DataIC50:  52nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM580188(US11498926, Example 1A)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318457(7-(3,5-Dimethylisoxazol-4-yl)-1-methyl-4-phenyl-4,...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318458(7-(3,5-Dimethylisoxazol-4-yl)-5-methyl-4-phenyl-4,...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318459(4-[7-(3,5-Dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tet...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318460(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-3-yl-4,5-d...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318461(7-(3,5-Dimethylisoxazol-4-yl)-4-(3-methoxyphenyl)-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318462(7-(3,5-Dimethylisoxazol-4-yl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318463(7-(3,5-Dimethylisoxazol-4-yl)-4-(2,4-difluoropheny...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318464(7-(3,5-Dimethylisoxazol-4-yl)-2-methyl-4-phenyl-4,...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318471(4-Cyclohexyl-7-(3,5-dimethylisoxazol-4-yl)-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318474(7-(3,5-Dimethylisoxazol-4-yl)-4-(1,3-thiazol-2-yl)...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318475(2-{2-[7-(3,5-Dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318476(Ethyl 7-(3,5-dimethylisoxazol-4-yl)-2-oxo-4-phenyl...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318479(7-(3,5-Dimethylisoxazol-4-yl)-N-isopropyl-4-phenyl...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318480(7-(3,5-Dimethylisoxazol-4-yl)-N-methyl-4-phenyl-4,...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318481(7-(3,5-Dimethylisoxazol-4-yl)-N-ethyl-4-phenyl-4,5...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318482(7-(3,5-Dimethylisoxazol-4-yl)-N,N-dimethyl-4-pheny...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318483(2-{[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM580219(US11498926, Example 30 | US11498926, Example 31)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM580219(US11498926, Example 30 | US11498926, Example 31)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318486(1-{[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318488(2-[[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318493(7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydro...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318495(7-(3,5-Dimethylisoxazol-4-yl)- 4-(4-fluorophenyl)-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318496(2-{2-[7-(3,5-Dimethylisoxazol- 4-yl)-2-oxo-1,2,4,5...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318497(2-{2-[7-(3,5-Dimethylisoxazol- 4-yl)-2-oxo-1,2,4,5...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318498(7-(3,5-Dimethylisoxazol-4-yl)-2- morpholin-4-yl-4-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318499(7-(3,5-Dimethylisoxazol-4-yl)-4- phenyl-2-pyrrolid...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318500(1-[7-(3,5-Dimethylisoxazol-4-yl)- 4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318501(7-(3,5-Dimethylisoxazol-4-yl)-4- phenyl-2-piperidi...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318502(1-[7-(3,5-Dimethylisoxazol-4-yl)- 4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318503(1-[7-(3,5-Dimethylisoxazol-4-yl)- 4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318504(1-[7-(3,5-Dimethylisoxazol-4-yl)- 4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318505(4-[7-(3,5-Dimethylisoxazol-4-yl)- 4-phenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318506(7-(3,5-Dimethylisoxazol-4-yl)-4-(1-oxidopyridin-2-...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318507(7-(3,5-Dimethylisoxazol-4-yl)-4-(5-fluoropyridin-2...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318509(7-(3,5-Dimethylisoxazol-4-yl)-2,4-diphenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM580250(US11498926, Example 42)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318511(7-(3,5-Dimethylisoxazol-4-yl)-4,9-diphenyl-4,5-dih...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM318513(9-Bromo-7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5...)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
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