Compile Data Set for Download or QSAR
Found 103 of affinity data for UniProtKB/TrEMBL: Q96T60
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553888(US11325905, Compound A12B4C16)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(CCc1c[nH]c3ccccc13)C2=O
Affinity DataIC50: 3.80E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553808(US11325905, Compound A70B4C3 | US11325905, Compoun...)
Show SMILES CC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C22H22N4O5/c1-2-19(27)18-13-12-17-20(22(29)24(21(17)28)15-6-4-3-5-7-15)25(18)23-14-8-10-16(11-9-14)26(30)31/h3-13,17-20,23,27H,2H2,1H3/t17?,18?,19-,20-/m0/s1
Affinity DataIC50: 3.90E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553886(US11325905, Compound A12B4C10)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(CN)cc1
Show InChI InChI=1S/C31H41N5O5/c1-2-3-4-5-6-7-8-9-10-28(37)27-20-19-26-29(35(27)33-23-13-17-25(18-14-23)36(40)41)31(39)34(30(26)38)24-15-11-22(21-32)12-16-24/h11-20,26-29,33,37H,2-10,21,32H2,1H3/t26?,27?,28-,29-/m0/s1
Affinity DataIC50: 4.40E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553899(US11325905, Compound A12B4C53)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(cc1)-c1ccon1
Show InChI InChI=1S/C33H39N5O6/c1-2-3-4-5-6-7-8-9-10-30(39)29-20-19-27-31(37(29)34-24-13-17-26(18-14-24)38(42)43)33(41)36(32(27)40)25-15-11-23(12-16-25)28-21-22-44-35-28/h11-22,27,29-31,34,39H,2-10H2,1H3/t27?,29?,30-,31-/m0/s1
Affinity DataIC50: 5.30E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553889(US11325905, Compound A12B4C17)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C33H44N4O8/c1-5-6-7-8-9-10-11-12-13-27(38)26-19-18-25-30(36(26)34-22-14-16-23(17-15-22)37(41)42)33(40)35(32(25)39)24-20-28(43-2)31(45-4)29(21-24)44-3/h14-21,25-27,30,34,38H,5-13H2,1-4H3/t25?,26?,27-,30-/m0/s1
Affinity DataIC50: 6.00E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553909(US11325905, Compound A12B27C3)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(Cl)cc1)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C30H38ClN3O3/c1-2-3-4-5-6-7-8-12-15-27(35)26-21-20-25-28(34(26)32-23-18-16-22(31)17-19-23)30(37)33(29(25)36)24-13-10-9-11-14-24/h9-11,13-14,16-21,25-28,32,35H,2-8,12,15H2,1H3/t25?,26?,27-,28-/m0/s1
Affinity DataIC50: 6.10E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553925(US11325905, Compound A44B29C50)
Show SMILES CS(=O)(=O)c1ccc(NN2[C@H]3[C@@H](C=C[C@@H]2[C@H](O)c2ccc(Br)cc2)C(=O)N(C3=O)c2ccc(cc2)N2CCNCC2)cc1
Show InChI InChI=1S/C31H32BrN5O5S/c1-43(41,42)25-12-6-22(7-13-25)34-37-27(29(38)20-2-4-21(32)5-3-20)15-14-26-28(37)31(40)36(30(26)39)24-10-8-23(9-11-24)35-18-16-33-17-19-35/h2-15,26-29,33-34,38H,16-19H2,1H3/t26-,27-,28+,29-/m1/s1
Affinity DataIC50: 6.20E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553893(US11325905, Compound A12B4C31)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(C)c(c1)C(C)=O
Show InChI InChI=1S/C33H42N4O6/c1-4-5-6-7-8-9-10-11-12-30(39)29-20-19-27-31(36(29)34-24-14-17-25(18-15-24)37(42)43)33(41)35(32(27)40)26-16-13-22(2)28(21-26)23(3)38/h13-21,27,29-31,34,39H,4-12H2,1-3H3/t27?,29?,30-,31-/m0/s1
Affinity DataIC50: 6.50E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553903(US11325905, Compound A12B4C63)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C35H42N4O5/c1-2-3-4-5-6-7-8-9-17-32(40)31-23-22-30-33(38(31)36-27-18-20-28(21-19-27)39(43)44)35(42)37(34(30)41)24-26-15-12-14-25-13-10-11-16-29(25)26/h10-16,18-23,30-33,36,40H,2-9,17,24H2,1H3/t30?,31?,32-,33-/m0/s1
Affinity DataIC50: 7.00E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553814(US11325905, Compound A89B4C3)
Show SMILES CCCCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C32H42N4O5/c1-2-3-4-5-6-7-8-9-10-14-17-29(37)28-23-22-27-30(32(39)34(31(27)38)25-15-12-11-13-16-25)35(28)33-24-18-20-26(21-19-24)36(40)41/h11-13,15-16,18-23,27-30,33,37H,2-10,14,17H2,1H3/t27?,28?,29-,30-/m0/s1
Affinity DataIC50: 8.00E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553929(US11325905, Compound A83B1C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1C=C[C@@H]2[C@H](N1Nc1ccccc1)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C32H29N3O4/c1-39-28-17-8-7-16-25(28)30(36)27-19-18-26-29(35(27)33-23-13-3-2-4-14-23)32(38)34(31(26)37)20-22-12-9-11-21-10-5-6-15-24(21)22/h2-19,26-27,29-30,33,36H,20H2,1H3/t26-,27-,29+,30-/m1/s1
Affinity DataIC50: 8.40E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553887(US11325905, Compound A12B4C15)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1OC
Show InChI InChI=1S/C31H40N4O6/c1-3-4-5-6-7-8-9-10-14-27(36)25-21-20-24-29(34(25)32-22-16-18-23(19-17-22)35(39)40)31(38)33(30(24)37)26-13-11-12-15-28(26)41-2/h11-13,15-21,24-25,27,29,32,36H,3-10,14H2,1-2H3/t24?,25?,27-,29-/m0/s1
Affinity DataIC50: 9.00E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553891(US11325905, Compound A12B4C23)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(F)cc1
Show InChI InChI=1S/C30H37FN4O5/c1-2-3-4-5-6-7-8-9-10-27(36)26-20-19-25-28(34(26)32-22-13-17-24(18-14-22)35(39)40)30(38)33(29(25)37)23-15-11-21(31)12-16-23/h11-20,25-28,32,36H,2-10H2,1H3/t25?,26?,27-,28-/m0/s1
Affinity DataIC50: 9.60E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553928(US11325905, Compound A83B4C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1C=C[C@@H]2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C32H28N4O6/c1-42-28-12-5-4-11-25(28)30(37)27-18-17-26-29(35(27)33-22-13-15-23(16-14-22)36(40)41)32(39)34(31(26)38)19-21-9-6-8-20-7-2-3-10-24(20)21/h2-18,26-27,29-30,33,37H,19H2,1H3/t26-,27-,29+,30-/m1/s1
Affinity DataIC50: 9.80E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553934(US11325905, Compound A83B38C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1CC[C@@H]2[C@H](N1C(=O)c1ccc(cc1)N(=O)=O)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C33H29N3O7/c1-43-28-12-5-4-11-25(28)30(37)27-18-17-26-29(35(27)31(38)21-13-15-23(16-14-21)36(41)42)33(40)34(32(26)39)19-22-9-6-8-20-7-2-3-10-24(20)22/h2-16,26-27,29-30,37H,17-19H2,1H3/t26-,27-,29+,30-/m1/s1
Affinity DataIC50: 1.00E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553897(US11325905, Compound A12B4C50)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C34H46N6O5/c1-2-3-4-5-6-7-8-9-10-31(41)30-20-19-29-32(39(30)36-25-11-13-28(14-12-25)40(44)45)34(43)38(33(29)42)27-17-15-26(16-18-27)37-23-21-35-22-24-37/h11-20,29-32,35-36,41H,2-10,21-24H2,1H3/t29?,30?,31-,32-/m0/s1
Affinity DataIC50: 1.19E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553914(US11325905, Compound A12B37C3)
Show SMILES CCCCCCCCCCC(O)C1C=CC2[C@H](N1C(N)c1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C31H40N4O5/c1-2-3-4-5-6-7-8-12-15-27(36)26-21-20-25-28(31(38)33(30(25)37)23-13-10-9-11-14-23)34(26)29(32)22-16-18-24(19-17-22)35(39)40/h9-11,13-14,16-21,25-29,36H,2-8,12,15,32H2,1H3/t25?,26?,27?,28-,29?/m0/s1
Affinity DataIC50: 1.20E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553920(US11325905, Compound A44B4C50)
Show SMILES OC(C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(cc1)N1CCNCC1)c1ccc(Br)cc1
Show InChI InChI=1S/C30H29BrN6O5/c31-20-3-1-19(2-4-20)28(38)26-14-13-25-27(36(26)33-21-5-7-24(8-6-21)37(41)42)30(40)35(29(25)39)23-11-9-22(10-12-23)34-17-15-32-16-18-34/h1-14,25-28,32-33,38H,15-18H2/t25?,26?,27-,28?/m0/s1
Affinity DataIC50: 1.30E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553877(US11325905, Compound A19B4C10)
Show SMILES NCc1ccc(cc1)N1C(=O)C2C=CC([C@@H](O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc3ccc(cc3)N(=O)=O)[C@@H]2C1=O
Show InChI InChI=1S/C29H23F6N5O5/c30-28(31,32)17-11-16(12-18(13-17)29(33,34)35)25(41)23-10-9-22-24(39(23)37-19-3-7-21(8-4-19)40(44)45)27(43)38(26(22)42)20-5-1-15(14-36)2-6-20/h1-13,22-25,37,41H,14,36H2/t22?,23?,24-,25-/m0/s1
Affinity DataIC50: 1.31E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553885(US11325905, Compound A12B4C5)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C37H44N4O5/c1-2-3-4-5-6-7-8-12-15-34(42)33-25-24-32-35(40(33)38-29-18-22-31(23-19-29)41(45)46)37(44)39(36(32)43)30-20-16-28(17-21-30)26-27-13-10-9-11-14-27/h9-11,13-14,16-25,32-35,38,42H,2-8,12,15,26H2,1H3/t32?,33?,34-,35-/m0/s1
Affinity DataIC50: 1.50E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553883(US11325905, Compound A85B4C10)
Show SMILES COc1cccc(c1)C([C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(CN)cc1)c1ccccc1
Show InChI InChI=1S/C35H33N5O6/c1-46-28-9-5-8-24(20-28)31(23-6-3-2-4-7-23)33(41)30-19-18-29-32(39(30)37-25-12-16-27(17-13-25)40(44)45)35(43)38(34(29)42)26-14-10-22(21-36)11-15-26/h2-20,29-33,37,41H,21,36H2,1H3/t29?,30?,31?,32-,33+/m0/s1
Affinity DataIC50: 1.50E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553915(US11325905, Compound A83C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1CC[C@@H]2[C@H](N1)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C26H26N2O4/c1-32-22-12-5-4-11-19(22)24(29)21-14-13-20-23(27-21)26(31)28(25(20)30)15-17-9-6-8-16-7-2-3-10-18(16)17/h2-12,20-21,23-24,27,29H,13-15H2,1H3/t20-,21-,23+,24-/m1/s1
Affinity DataIC50: 1.50E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553932(US11325905, Compound A83B4C69)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1C=C[C@@H]2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(Cc1cccc3cccnc13)C2=O
Show InChI InChI=1S/C31H27N5O6/c1-42-26-10-3-2-9-23(26)29(37)25-16-15-24-28(35(25)33-21-11-13-22(14-12-21)36(40)41)31(39)34(30(24)38)18-20-7-4-6-19-8-5-17-32-27(19)20/h2-17,24-25,28-29,33,37H,18H2,1H3/t24-,25-,28+,29-/m1/s1
Affinity DataIC50: 1.60E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553935(US11325905, Compound A44B4C66)
Show SMILES OC(C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(cc1)N1CCOCC1)c1ccc(Br)cc1
Show InChI InChI=1S/C30H28BrN5O6/c31-20-3-1-19(2-4-20)28(37)26-14-13-25-27(35(26)32-21-5-7-24(8-6-21)36(40)41)30(39)34(29(25)38)23-11-9-22(10-12-23)33-15-17-42-18-16-33/h1-14,25-28,32,37H,15-18H2/t25?,26?,27-,28?/m0/s1
Affinity DataIC50: 1.70E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553917(US11325905, Compound A44B27C3)
Show SMILES OC(C1C=CC2[C@H](N1Nc1ccc(Cl)cc1)C(=O)N(C2=O)c1ccccc1)c1ccc(Br)cc1
Show InChI InChI=1S/C26H21BrClN3O3/c27-17-8-6-16(7-9-17)24(32)22-15-14-21-23(31(22)29-19-12-10-18(28)11-13-19)26(34)30(25(21)33)20-4-2-1-3-5-20/h1-15,21-24,29,32H/t21?,22?,23-,24?/m0/s1
Affinity DataIC50: 1.80E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553816(US11325905, Compound A96B4C3)
Show SMILES Cc1cc(ccc1Br)[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C27H23BrN4O5/c1-16-15-17(7-13-22(16)28)25(33)23-14-12-21-24(27(35)30(26(21)34)19-5-3-2-4-6-19)31(23)29-18-8-10-20(11-9-18)32(36)37/h2-15,21,23-25,29,33H,1H3/t21?,23?,24-,25-/m0/s1
Affinity DataIC50: 1.90E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553933(US11325905, Compound A83B37C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1C=C[C@@H]2[C@H](N1Cc1ccc(cc1)N(=O)=O)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C33H29N3O6/c1-42-29-12-5-4-11-26(29)31(37)28-18-17-27-30(34(28)19-21-13-15-24(16-14-21)36(40)41)33(39)35(32(27)38)20-23-9-6-8-22-7-2-3-10-25(22)23/h2-18,27-28,30-31,37H,19-20H2,1H3/t27-,28-,30+,31-/m1/s1
Affinity DataIC50: 1.94E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553924(US11325905, Compound A83B29C63)
Show SMILES COc1ccccc1[C@@H](O)[C@H]1C=C[C@@H]2[C@H](N1Nc1ccc(cc1)S(C)=O)C(=O)N(Cc1cccc3ccccc13)C2=O
Show InChI InChI=1S/C33H31N3O5S/c1-41-29-13-6-5-12-26(29)31(37)28-19-18-27-30(36(28)34-23-14-16-24(17-15-23)42(2)40)33(39)35(32(27)38)20-22-10-7-9-21-8-3-4-11-25(21)22/h3-19,27-28,30-31,34,37H,20H2,1-2H3/t27-,28-,30+,31-,42?/m1/s1
Affinity DataIC50: 2.00E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553807(US11325905, Compound A44B4C3)
Show SMILES O[C@H](C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1)c1ccc(Br)cc1
Show InChI InChI=1S/C26H21BrN4O5/c27-17-8-6-16(7-9-17)24(32)22-15-14-21-23(26(34)29(25(21)33)19-4-2-1-3-5-19)30(22)28-18-10-12-20(13-11-18)31(35)36/h1-15,21-24,28,32H/t21?,22?,23-,24-/m0/s1
Affinity DataIC50: 2.20E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553919(US11325905, Compound A44B4C60)
Show SMILES OC(C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(Cc1ccccn1)C2=O)c1ccc(Br)cc1
Show InChI InChI=1S/C26H22BrN5O5/c27-17-6-4-16(5-7-17)24(33)22-13-12-21-23(31(22)29-18-8-10-20(11-9-18)32(36)37)26(35)30(25(21)34)15-19-3-1-2-14-28-19/h1-14,21-24,29,33H,15H2/t21?,22?,23-,24?/m0/s1
Affinity DataIC50: 2.20E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553812(US11325905, Compound A83B4C3)
Show SMILES CC(=O)c1ccccc1[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C28H24N4O6/c1-17(33)21-9-5-6-10-22(21)26(34)24-16-15-23-25(28(36)30(27(23)35)19-7-3-2-4-8-19)31(24)29-18-11-13-20(14-12-18)32(37)38/h2-16,23-26,29,34H,1H3/t23?,24?,25-,26-/m0/s1
Affinity DataIC50: 3.00E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553926(US11325905, Compound A12B29C60)
Show SMILES CCCCCCCCCCC(O)C1C=CC2[C@H](N1Nc1ccc(cc1)S(C)(=O)=O)C(=O)N(Cc1ccccn1)C2=O
Show InChI InChI=1S/C31H42N4O5S/c1-3-4-5-6-7-8-9-10-14-28(36)27-20-19-26-29(31(38)34(30(26)37)22-24-13-11-12-21-32-24)35(27)33-23-15-17-25(18-16-23)41(2,39)40/h11-13,15-21,26-29,33,36H,3-10,14,22H2,1-2H3/t26?,27?,28?,29-/m0/s1
Affinity DataIC50: 3.40E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553908(US11325905, Compound A12B12C3)
Show SMILES CCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)C#N)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C31H38N4O3/c1-2-3-4-5-6-7-8-12-15-28(36)27-21-20-26-29(35(27)33-24-18-16-23(22-32)17-19-24)31(38)34(30(26)37)25-13-10-9-11-14-25/h9-11,13-14,16-21,26-29,33,36H,2-8,12,15H2,1H3/t26?,27?,28-,29-/m0/s1
Affinity DataIC50: 3.94E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553923(US11325905, Compound A44B29C60)
Show SMILES CS(=O)(=O)c1ccc(NN2[C@H]3[C@@H](C=C[C@@H]2[C@H](O)c2ccc(Br)cc2)C(=O)N(Cc2ccccn2)C3=O)cc1
Show InChI InChI=1S/C27H25BrN4O5S/c1-38(36,37)21-11-9-19(10-12-21)30-32-23(25(33)17-5-7-18(28)8-6-17)14-13-22-24(32)27(35)31(26(22)34)16-20-4-2-3-15-29-20/h2-15,22-25,30,33H,16H2,1H3/t22-,23-,24+,25-/m1/s1
Affinity DataIC50: 4.00E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553808(US11325905, Compound A70B4C3 | US11325905, Compoun...)
Show SMILES CC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C22H22N4O5/c1-2-19(27)18-13-12-17-20(22(29)24(21(17)28)15-6-4-3-5-7-15)25(18)23-14-8-10-16(11-9-14)26(30)31/h3-13,17-20,23,27H,2H2,1H3/t17?,18?,19-,20-/m0/s1
Affinity DataIC50: 4.80E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553806(US11325905, Compound A5B4C3)
Show SMILES CN(C)c1ccc(cc1)[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C28H27N5O5/c1-30(2)20-12-8-18(9-13-20)26(34)24-17-16-23-25(28(36)31(27(23)35)21-6-4-3-5-7-21)32(24)29-19-10-14-22(15-11-19)33(37)38/h3-17,23-26,29,34H,1-2H3/t23?,24?,25-,26-/m0/s1
Affinity DataKd:  550nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553807(US11325905, Compound A44B4C3)
Show SMILES O[C@H](C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1)c1ccc(Br)cc1
Show InChI InChI=1S/C26H21BrN4O5/c27-17-8-6-16(7-9-17)24(32)22-15-14-21-23(26(34)29(25(21)33)19-4-2-1-3-5-19)30(22)28-18-10-12-20(13-11-18)31(35)36/h1-15,21-24,28,32H/t21?,22?,23-,24-/m0/s1
Affinity DataKd:  150nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553808(US11325905, Compound A70B4C3 | US11325905, Compoun...)
Show SMILES CC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C22H22N4O5/c1-2-19(27)18-13-12-17-20(22(29)24(21(17)28)15-6-4-3-5-7-15)25(18)23-14-8-10-16(11-9-14)26(30)31/h3-13,17-20,23,27H,2H2,1H3/t17?,18?,19-,20-/m0/s1
Affinity DataKd:  1.05E+3nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553810(US11325905, Compound A76B4C3)
Show SMILES CCCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C31H40N4O5/c1-2-3-4-5-6-7-8-9-13-16-28(36)27-22-21-26-29(31(38)33(30(26)37)24-14-11-10-12-15-24)34(27)32-23-17-19-25(20-18-23)35(39)40/h10-12,14-15,17-22,26-29,32,36H,2-9,13,16H2,1H3/t26?,27?,28-,29-/m0/s1
Affinity DataKd:  200nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553808(US11325905, Compound A70B4C3 | US11325905, Compoun...)
Show SMILES CC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C22H22N4O5/c1-2-19(27)18-13-12-17-20(22(29)24(21(17)28)15-6-4-3-5-7-15)25(18)23-14-8-10-16(11-9-14)26(30)31/h3-13,17-20,23,27H,2H2,1H3/t17?,18?,19-,20-/m0/s1
Affinity DataKd:  240nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553812(US11325905, Compound A83B4C3)
Show SMILES CC(=O)c1ccccc1[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C28H24N4O6/c1-17(33)21-9-5-6-10-22(21)26(34)24-16-15-23-25(28(36)30(27(23)35)19-7-3-2-4-8-19)31(24)29-18-11-13-20(14-12-18)32(37)38/h2-16,23-26,29,34H,1H3/t23?,24?,25-,26-/m0/s1
Affinity DataKd:  220nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553814(US11325905, Compound A89B4C3)
Show SMILES CCCCCCCCCCCC[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C32H42N4O5/c1-2-3-4-5-6-7-8-9-10-14-17-29(37)28-23-22-27-30(32(39)34(31(27)38)25-15-12-11-13-16-25)35(28)33-24-18-20-26(21-19-24)36(40)41/h11-13,15-16,18-23,27-30,33,37H,2-10,14,17H2,1H3/t27?,28?,29-,30-/m0/s1
Affinity DataKd:  450nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553815(US11325905, Compound A95B4C3)
Show SMILES O[C@H](C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1)c1ccc(cc1)C(=O)c1ccccc1
Show InChI InChI=1S/C33H26N4O6/c38-30(21-7-3-1-4-8-21)22-11-13-23(14-12-22)31(39)28-20-19-27-29(33(41)35(32(27)40)25-9-5-2-6-10-25)36(28)34-24-15-17-26(18-16-24)37(42)43/h1-20,27-29,31,34,39H/t27?,28?,29-,31-/m0/s1
Affinity DataKd:  250nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553816(US11325905, Compound A96B4C3)
Show SMILES Cc1cc(ccc1Br)[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C27H23BrN4O5/c1-16-15-17(7-13-22(16)28)25(33)23-14-12-21-24(27(35)30(26(21)34)19-5-3-2-4-6-19)31(23)29-18-8-10-20(11-9-18)32(36)37/h2-15,21,23-25,29,33H,1H3/t21?,23?,24-,25-/m0/s1
Affinity DataKd:  160nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553827(US11325905, Compound A98B4C3)
Show SMILES CCCCCCOc1cc(ccc1Br)[C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1
Show InChI InChI=1S/C32H33BrN4O6/c1-2-3-4-8-19-43-28-20-21(11-17-26(28)33)30(38)27-18-16-25-29(32(40)35(31(25)39)23-9-6-5-7-10-23)36(27)34-22-12-14-24(15-13-22)37(41)42/h5-7,9-18,20,25,27,29-30,34,38H,2-4,8,19H2,1H3/t25?,27?,29-,30-/m0/s1
Affinity DataKd:  240nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553830(US11325905, Compound A99B4C3)
Show SMILES O[C@H](C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccccc1)c1ccc(Br)c(CCC=C)c1
Show InChI InChI=1S/C30H27BrN4O5/c1-2-3-7-19-18-20(10-16-25(19)31)28(36)26-17-15-24-27(30(38)33(29(24)37)22-8-5-4-6-9-22)34(26)32-21-11-13-23(14-12-21)35(39)40/h2,4-6,8-18,24,26-28,32,36H,1,3,7H2/t24?,26?,27-,28-/m0/s1
Affinity DataKd:  160nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553877(US11325905, Compound A19B4C10)
Show SMILES NCc1ccc(cc1)N1C(=O)C2C=CC([C@@H](O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc3ccc(cc3)N(=O)=O)[C@@H]2C1=O
Show InChI InChI=1S/C29H23F6N5O5/c30-28(31,32)17-11-16(12-18(13-17)29(33,34)35)25(41)23-10-9-22-24(39(23)37-19-3-7-21(8-4-19)40(44)45)27(43)38(26(22)42)20-5-1-15(14-36)2-6-20/h1-13,22-25,37,41H,14,36H2/t22?,23?,24-,25-/m0/s1
Affinity DataKd:  105nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553878(US11325905, Compound A26B4C10)
Show SMILES NCc1ccc(cc1)N1C(=O)C2C=CC([C@@H](O)C(c3ccccc3)c3ccccc3)N(Nc3ccc(cc3)N(=O)=O)[C@@H]2C1=O
Show InChI InChI=1S/C34H31N5O5/c35-21-22-11-15-26(16-12-22)37-33(41)28-19-20-29(32(40)30(23-7-3-1-4-8-23)24-9-5-2-6-10-24)38(31(28)34(37)42)36-25-13-17-27(18-14-25)39(43)44/h1-20,28-32,36,40H,21,35H2/t28?,29?,31-,32+/m0/s1
Affinity DataKd:  650nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553879(US11325905, Compound A37B4C10 | US11325905, Compou...)
Show SMILES Cc1ccc(cc1)C([C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(CN)cc1)c1ccccc1
Show InChI InChI=1S/C35H33N5O5/c1-22-7-11-25(12-8-22)31(24-5-3-2-4-6-24)33(41)30-20-19-29-32(39(30)37-26-13-17-28(18-14-26)40(44)45)35(43)38(34(29)42)27-15-9-23(21-36)10-16-27/h2-20,29-33,37,41H,21,36H2,1H3/t29?,30?,31?,32-,33+/m0/s1
Affinity DataKd:  320nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetBifunctional polynucleotide phosphatase/kinase(Human)
The Governors of the University of Alberta

US Patent
LigandPNGBDBM553880(US11325905, Compound A43B4C10)
Show SMILES CC1(C)C2CC1C=C(C2)C([C@H](O)C1C=CC2[C@H](N1Nc1ccc(cc1)N(=O)=O)C(=O)N(C2=O)c1ccc(CN)cc1)c1ccccc1
Show InChI InChI=1S/C37H39N5O5/c1-37(2)25-18-24(19-26(37)20-25)32(23-6-4-3-5-7-23)34(43)31-17-16-30-33(41(31)39-27-10-14-29(15-11-27)42(46)47)36(45)40(35(30)44)28-12-8-22(21-38)9-13-28/h3-18,25-26,30-34,39,43H,19-21,38H2,1-2H3/t25?,26?,30?,31?,32?,33-,34+/m0/s1
Affinity DataKd:  450nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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