Compile Data Set for Download or QSAR
Found 3 of affinity data for UniProtKB/TrEMBL: Q8R492
TargetFibroblast activation protein(Rat)
PRAXIS BIOTECH LLC

US Patent
LigandPNGBDBM50050513((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)
Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
Affinity DataIC50: 1.00E+3nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
TargetFibroblast activation protein(Rat)
PRAXIS BIOTECH LLC

US Patent
LigandPNGBDBM581063(US11504364, Compound 2)
Show SMILES FC1(F)C[C@@H](C#N)N(C1)C(=O)CNC(=O)c1ccnc2ccc(cc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H17ClF2N4O2/c24-16-4-1-14(2-5-16)15-3-6-20-19(9-15)18(7-8-28-20)22(32)29-12-21(31)30-13-23(25,26)10-17(30)11-27/h1-9,17H,10,12-13H2,(H,29,32)/t17-/m0/s1
Affinity DataIC50: 1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFibroblast activation protein(Rat)
PRAXIS BIOTECH LLC

US Patent
LigandPNGBDBM50009366(CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...)
Show SMILES FC1(F)C[C@@H](C#N)N(C1)C(=O)CNC(=O)c1ccnc2ccccc12
Show InChI InChI=1S/C17H14F2N4O2/c18-17(19)7-11(8-20)23(10-17)15(24)9-22-16(25)13-5-6-21-14-4-2-1-3-12(13)14/h1-6,11H,7,9-10H2,(H,22,25)/t11-/m0/s1
Affinity DataIC50: 1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair