Compile Data Set for Download or QSAR
Found 16 of affinity data for UniProtKB/TrEMBL: Q9UJQ4
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585366(US11530209, Compound A1)
Show SMILES Oc1ccc2ccccc2c1-c1nc2ccccn2c1NC1CC1
Show InChI InChI=1S/C20H17N3O/c24-16-11-8-13-5-1-2-6-15(13)18(16)19-20(21-14-9-10-14)23-12-4-3-7-17(23)22-19/h1-8,11-12,14,21,24H,9-10H2
Affinity DataIC50: 109nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585370(US11530209, Compound A12)
Show SMILES CC(C)(C)Nc1c(nc2ccccn12)-c1c(O)ccc2ccccc12
Show InChI InChI=1S/C21H21N3O/c1-21(2,3)23-20-19(22-17-10-6-7-13-24(17)20)18-15-9-5-4-8-14(15)11-12-16(18)25/h4-13,23,25H,1-3H3
Affinity DataIC50: 162nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585372(US11530209, Compound E2)
Show SMILES COc1cccc(CNc2c(nc3cnccn23)-c2c(O)ccc3ccccc23)c1
Show InChI InChI=1S/C24H20N4O2/c1-30-18-7-4-5-16(13-18)14-26-24-23(27-21-15-25-11-12-28(21)24)22-19-8-3-2-6-17(19)9-10-20(22)29/h2-13,15,26,29H,14H2,1H3
Affinity DataIC50: 288nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585371(US11530209, Compound E1)
Show SMILES Oc1ccc2ccccc2c1-c1nc2cnccn2c1NC1CC1
Show InChI InChI=1S/C19H16N4O/c24-15-8-5-12-3-1-2-4-14(12)17(15)18-19(21-13-6-7-13)23-10-9-20-11-16(23)22-18/h1-5,8-11,13,21,24H,6-7H2
Affinity DataIC50: 335nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585375(US11530209, Compound E6)
Show SMILES COCCNc1c(nc2cnccn12)-c1c(O)ccc2ccccc12
Show InChI InChI=1S/C19H18N4O2/c1-25-11-9-21-19-18(22-16-12-20-8-10-23(16)19)17-14-5-3-2-4-13(14)6-7-15(17)24/h2-8,10,12,21,24H,9,11H2,1H3
Affinity DataIC50: 434nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585378(US11530209, Compound E9)
Show SMILES Oc1ccc2ccccc2c1-c1nc2cnccn2c1Nc1ccc(cc1)C#N
Show InChI InChI=1S/C23H15N5O/c24-13-15-5-8-17(9-6-15)26-23-22(27-20-14-25-11-12-28(20)23)21-18-4-2-1-3-16(18)7-10-19(21)29/h1-12,14,26,29H
Affinity DataIC50: 498nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585380(US11530209, Compound E11)
Show SMILES Oc1ccc2ccccc2c1-c1nc2cnccn2c1NCc1ccccc1
Show InChI InChI=1S/C23H18N4O/c28-19-11-10-17-8-4-5-9-18(17)21(19)22-23(25-14-16-6-2-1-3-7-16)27-13-12-24-15-20(27)26-22/h1-13,15,25,28H,14H2
Affinity DataIC50: 594nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585379(US11530209, Compound E10)
Show SMILES Oc1ccc2ccccc2c1-c1nc2cnccn2c1NC1CCCCC1
Show InChI InChI=1S/C22H22N4O/c27-18-11-10-15-6-4-5-9-17(15)20(18)21-22(24-16-7-2-1-3-8-16)26-13-12-23-14-19(26)25-21/h4-6,9-14,16,24,27H,1-3,7-8H2
Affinity DataIC50: 616nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585374(US11530209, Compound E5)
Show SMILES COc1ccc(Nc2c(nc3cnccn23)-c2c(O)ccc3ccccc23)cc1
Show InChI InChI=1S/C23H18N4O2/c1-29-17-9-7-16(8-10-17)25-23-22(26-20-14-24-12-13-27(20)23)21-18-5-3-2-4-15(18)6-11-19(21)28/h2-14,25,28H,1H3
Affinity DataIC50: 619nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585377(US11530209, Compound E8)
Show SMILES COC(=O)c1cccc(Nc2c(nc3cnccn23)-c2c(O)ccc3ccccc23)c1
Show InChI InChI=1S/C24H18N4O3/c1-31-24(30)16-6-4-7-17(13-16)26-23-22(27-20-14-25-11-12-28(20)23)21-18-8-3-2-5-15(18)9-10-19(21)29/h2-14,26,29H,1H3
Affinity DataIC50: 623nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585381(US11530209, Compound E12)
Show SMILES CC(C)(C)Nc1c(nc2cnccn12)-c1c(O)ccc2ccccc12
Show InChI InChI=1S/C20H20N4O/c1-20(2,3)23-19-18(22-16-12-21-10-11-24(16)19)17-14-7-5-4-6-13(14)8-9-15(17)25/h4-12,23,25H,1-3H3
Affinity DataIC50: 783nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585373(US11530209, Compound E4)
Show SMILES Oc1ccc2ccccc2c1-c1nc2cnccn2c1NCCN1CCOCC1
Show InChI InChI=1S/C22H23N5O2/c28-18-6-5-16-3-1-2-4-17(16)20(18)21-22(27-10-7-23-15-19(27)25-21)24-8-9-26-11-13-29-14-12-26/h1-7,10,15,24,28H,8-9,11-14H2
Affinity DataIC50: 1.36E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585369(US11530209, Compound A11)
Show SMILES Oc1ccc2ccccc2c1-c1nc2ccccn2c1NCc1ccccc1
Show InChI InChI=1S/C24H19N3O/c28-20-14-13-18-10-4-5-11-19(18)22(20)23-24(25-16-17-8-2-1-3-9-17)27-15-7-6-12-21(27)26-23/h1-15,25,28H,16H2
Affinity DataIC50: 1.51E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585367(US11530209, Compound A4)
Show SMILES Oc1ccc2ccccc2c1-c1nc2ccccn2c1NCCN1CCOCC1
Show InChI InChI=1S/C23H24N4O2/c28-19-9-8-17-5-1-2-6-18(17)21(19)22-23(27-11-4-3-7-20(27)25-22)24-10-12-26-13-15-29-16-14-26/h1-9,11,24,28H,10,12-16H2
Affinity DataIC50: 2.23E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585376(US11530209, Compound E7)
Show SMILES COc1ccc(CCNc2c(nc3cnccn23)-c2c(O)ccc3ccccc23)cc1OC
Show InChI InChI=1S/C26H24N4O3/c1-32-21-10-7-17(15-22(21)33-2)11-12-28-26-25(29-23-16-27-13-14-30(23)26)24-19-6-4-3-5-18(19)8-9-20(24)31/h3-10,13-16,28,31H,11-12H2,1-2H3
Affinity DataIC50: 2.49E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSal-like protein 4(Human)
DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN''S HOSPITAL, INC.

US Patent
LigandPNGBDBM585368(US11530209, Compound A10)
Show SMILES Oc1ccc2ccccc2c1-c1nc2ccccn2c1NC1CCCCC1
Show InChI InChI=1S/C23H23N3O/c27-19-14-13-16-8-4-5-11-18(16)21(19)22-23(24-17-9-2-1-3-10-17)26-15-7-6-12-20(26)25-22/h4-8,11-15,17,24,27H,1-3,9-10H2
Affinity DataIC50: 2.77E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid