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TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705092BDBM705092(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(6-((R)-...)
Affinity DataIC50: 0.0330nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704933BDBM704933(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) | US20240376097...)
Affinity DataIC50: 0.0410nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705093BDBM705093(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(6-((R)-...)
Affinity DataIC50: 0.0410nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705030BDBM705030(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(6-((R)-4...)
Affinity DataIC50: 0.0450nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705070BDBM705070(4-(6-((R)-4-((5,6- dimethoxypyridin-3-yl)methyl)-2...)
Affinity DataIC50: 0.0470nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705091BDBM705091(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0470nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704992BDBM704992(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-((R o...)
Affinity DataIC50: 0.0490nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705059BDBM705059(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0500nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705150BDBM705150(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0520nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705149BDBM705149(4-(6-((R)-4-((3,3-dimethy]-2,3- dihydro-[1,4]dioxi...)
Affinity DataIC50: 0.0570nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705054BDBM705054(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-(4-((...)
Affinity DataIC50: 0.0610nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705074BDBM705074(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0620nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705136BDBM705136(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0690nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705177BDBM705177(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0700nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705025BDBM705025(4-(6-((R)-4-(3,4-dimethoxybenzyl)-2-(2-isopropylph...)
Affinity DataIC50: 0.0720nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705064BDBM705064(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-(4-((...)
Affinity DataIC50: 0.0720nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705203BDBM705203(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-(((5...)
Affinity DataIC50: 0.0770nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705187BDBM705187(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0790nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704983BDBM704983(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0800nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705066BDBM705066(4-(2-((R)-4-(3,4-bis(methoxy-d3) benzyl)-2-(2-isop...)
Affinity DataIC50: 0.0800nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705144BDBM705144(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0810nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705069BDBM705069(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0830nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704925BDBM704925(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N- (((R)-3-...)
Affinity DataIC50: 0.0840nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704989BDBM704989(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-(4-(3...)
Affinity DataIC50: 0.0840nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705031BDBM705031(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.0860nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705065BDBM705065(4-(6-((R)-4-(3,4-bis(methoxy-d3) benzyl)-2-(2-isop...)
Affinity DataIC50: 0.0890nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704924BDBM704924(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N- ((4-((((...)
Affinity DataIC50: 0.0900nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705172BDBM705172(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(6-((R)-...)
Affinity DataIC50: 0.0900nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705199BDBM705199(N-((4-((((S)-1,4-dioxan-2-yl)methyl)amino)-3-nitro...)
Affinity DataIC50: 0.0940nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705188BDBM705188(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.0950nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705079BDBM705079((R)-2-((1H-pyrrolo[2,3-b]pyridin- 5-yl)oxy)-N-((4-...)
Affinity DataIC50: 0.100nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704981BDBM704981(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-(4-((...)
Affinity DataIC50: 0.100nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705076BDBM705076(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.100nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704961BDBM704961(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-((R o...)
Affinity DataIC50: 0.100nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704945BDBM704945((R or S)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705197BDBM705197(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-((((1...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705077BDBM705077(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705184BDBM705184(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705013BDBM705013(4-(2-((R)-4-(3,4-dimethoxybenzyl)-2-(2-isopropylph...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705198BDBM705198(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N- | US2024...)
Affinity DataIC50: 0.110nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705047BDBM705047(2-((3-chloro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-4...)
Affinity DataIC50: 0.120nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705090BDBM705090(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.120nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704932BDBM704932(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.120nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 704920BDBM704920(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N- ((4-((((...)
Affinity DataIC50: 0.120nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705179BDBM705179(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.120nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705135BDBM705135(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.130nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705173BDBM705173(2-((3-fluoro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-N...)
Affinity DataIC50: 0.130nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705052BDBM705052(2-((3-chloro-1H-pyrrolo[2,3-b] pyridin-5-yl)oxy)-4...)
Affinity DataIC50: 0.140nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705132BDBM705132(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.140nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 705156BDBM705156(2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-N-((4-((((...)
Affinity DataIC50: 0.140nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

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