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Found 27 of ic50 for UniProtKB: A0A5B7VGE2
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  24nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18231(2,4-diamino-5-deazapteridine, 2 | 7-[3-({2,4-diami...)
Affinity DataIC50:  270nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18239(2,4-diamino-5-deazapteridine, 8 | Piritrexim analo...)
Affinity DataIC50:  350nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18227(2,4-diamino-5-deazapteridine, 6 | 6-[3-({2,4-diami...)
Affinity DataIC50:  510nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18225(2,4-diamino-5-deazapteridine, 4 | 4-[3-({2,4-diami...)
Affinity DataIC50:  600nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18238(2,4-diamino-5-deazapteridine, 7 | Piritrexim analo...)
Affinity DataIC50:  880nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18499(6-{[(2-bromo-3,4,5-trimethoxyphenyl)amino]methyl}q...)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18226(2,4-diamino-5-deazapteridine, 5 | 5-[3-({2,4-diami...)
Affinity DataIC50:  1.67E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  1.85E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18230(2,4-diamino-5-deazapteridine, 10 | 6-[3-({2,4-diam...)
Affinity DataIC50:  1.90E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18502(6-{[(6-chloronaphthalen-2-yl)(methyl)amino]methyl}...)
Affinity DataIC50:  2.26E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18500(6-{[(6,7-dichloronaphthalen-2-yl)amino]methyl}pter...)
Affinity DataIC50:  4.82E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18501(6-{[(6-chloronaphthalen-2-yl)amino]methyl}pteridin...)
Affinity DataIC50:  6.32E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18503(6-{[(5,7-dichloronaphthalen-2-yl)amino]methyl}pter...)
Affinity DataIC50:  7.58E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18506(6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...)
Affinity DataIC50:  1.67E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18504(6-{[(5,7-dichloronaphthalen-2-yl)(methyl)amino]met...)
Affinity DataIC50:  1.76E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18508(5-[(5-iodo-2-methoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  3.73E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  4.30E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18509(7-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)
Affinity DataIC50:  6.93E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18510(5-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)
Affinity DataIC50:  7.37E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18511(6-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)
Affinity DataIC50:  1.50E+5nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18507(5-[2-(3,4,5-trimethoxyphenyl)ethyl]-7H-pyrrolo[2,3...)
Affinity DataIC50:  2.52E+5nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18505(6-{[(5,7-dichloronaphthalen-2-yl)(methyl)amino]met...)
Affinity DataIC50: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18515(1,3-diazatetraphene-2,4-diamine | Diaminonaphthoqu...)
Affinity DataIC50: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18513(1,3-diazatetraphene-2,4-diamine | Diaminonaphthoqu...)
Affinity DataIC50: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18514(4,6-diazatetracyclo[8.8.0.0^{2,7}.0^{11,16}]octade...)
Affinity DataIC50: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed