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Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341250BDBM50341250(N-{(3R,5R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-...)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341249BDBM50341249(1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H...)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139819BDBM139819(US8895581, III-5)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139837BDBM139837(US8895581, III-23)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105303BDBM105303(US8575203, I-70)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139798BDBM139798(US8895581, II-19)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105308BDBM105308(US8575203, I-75)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139785BDBM139785(US8895581, II-6)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139796BDBM139796(US8895581, II-17)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139828BDBM139828(US8895581, III-14)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139765BDBM139765(US8895581, I-1)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139845BDBM139845(US8895581, III-31)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139840BDBM139840(US8895581, III-26)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105283BDBM105283(US8575203, I-50)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341241BDBM50341241((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105294BDBM105294(US8575203, I-61)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105358BDBM105358(US8575203, I-125)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139789BDBM139789(US8895581, II-20 | US8895581, II-13 | US8895581, I...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105357BDBM105357(US8575203, I-124)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139800BDBM139800(US8895581, II-21)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105356BDBM105356(US8575203, I-123)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105295BDBM105295(US8575203, I-62)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139809BDBM139809(US8895581, II-30)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105305BDBM105305(US8575203, I-72)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139820BDBM139820(US8895581, III-6)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105367BDBM105367(US8575203, I-125.9)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105309BDBM105309(US8575203, I-76)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139816BDBM139816(US8895581, III-2)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105376BDBM105376(US8575203, I-125.18)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105375BDBM105375(US8575203, I-125.17)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105379BDBM105379(US8575203, I-125.21)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139768BDBM139768(US8895581, I-4)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139842BDBM139842(US8895581, III-28)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139780BDBM139780(US8895581, II-1)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105263BDBM105263(US8575203, I-30)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139774BDBM139774(US8895581, I-10)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105273BDBM105273(US8575203, I-40)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139788BDBM139788(US8895581, II-9)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139789BDBM139789(US8895581, II-20 | US8895581, II-13 | US8895581, I...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139782BDBM139782(US8895581, II-3)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139846BDBM139846(US8895581, III-32)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139847BDBM139847(US8895581, III-33)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139789BDBM139789(US8895581, II-20 | US8895581, II-13 | US8895581, I...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105284BDBM105284(US8575203, I-51)
Affinity DataIC50: 2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401910BDBM50401910(CHEMBL2207217)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [gamma33P]ATP from human TBK1 expressed in insect sf21 cells measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341243BDBM50341243((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341243BDBM50341243((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 117036BDBM117036(US8664236, A16 | US9238651, A16)
Affinity DataIC50: 2.60nMpH: 8.0 T: 2°CAssay Description:The cellular assay for the determination of the PDK1 kinase activity is carried out as a Luminex assay in the 96-well format. PC3 cells are sown at 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105289BDBM105289(US8575203, I-56)
Affinity DataIC50: 3nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 105260BDBM105260(US8575203, I-27)
Affinity DataIC50: 3nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

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