Compile Data Set for Download or QSAR
Report error Found 15 of ec50 for UniProtKB: P48736
LigandChemical structure of BindingDB Monomer ID 50042924BDBM50042924(CHEMBL1229535)
Affinity DataEC50:  4nMAssay Description:Inhibition of PI3K gamma (unknown origin) by membrane capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50341209BDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataEC50:  5.70nMAssay Description:Inhibition of PI3K gamma (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 185147BDBM185147(BGT-226 | (Z)-but-2-enedioic acid;8-(6-methoxypyri...)
Affinity DataEC50:  38nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataEC50:  51nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataEC50:  51nMAssay Description:Inhibition of PI3K-gamma (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 92862BDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataEC50:  67nMAssay Description:Inhibition of PI3K-gamma (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 92862BDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataEC50:  67nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50653061BDBM50653061(CHEMBL5723005)
Affinity DataEC50:  171nMAssay Description:Inhibition of PI3K gamma (unknown origin) by drug competition for substrate binding based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 315499BDBM315499(US10172858, Table 1.22)
Affinity DataEC50:  221nMAssay Description:Inhibition of PI3K gamma (unknown origin) by PIP3 production detection based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 198031BDBM198031(US9221795, 27)
Affinity DataEC50:  404nMAssay Description:Inhibition of PI3K p110gamma in human basophil assessed as reduction in fMLP-induced basophil activation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 198031BDBM198031(US9221795, 27)
Affinity DataEC50:  581nMAssay Description:Inhibition of PI3K p110gamma in human basophil assessed as reduction in fMLP-induced basophil activation in presence of 25% serum by flow cytometry a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50156294BDBM50156294(CHEMBL3781415)
Affinity DataEC50:  3.04E+3nMAssay Description:Inhibition of PI3K gamma (unknown origin) by membrane capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50468940BDBM50468940(CHEMBL4291904)
Affinity DataEC50:  9.89E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50467448BDBM50467448(CHEMBL4280001)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed