Compile Data Set for Download or QSAR
Report error Found 7664 of ki for UniProtKB: P35372
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292912BDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataKi:  0.00130nMAssay Description:Displacement of [3H]-DAMGO from human HA-tagged mu-opioid receptor expressed in HEK293 cells after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402775BDBM50402775(CHEMBL2208351)
Affinity DataKi:  0.00160nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648331BDBM50648331(CHEMBL5613639)
Affinity DataKi:  0.00200nMAssay Description:Binding affinity to human mu-opioid receptor extracted from CHO cell membrane assessed as inhibition constant incubated for 60 mins in presence of [3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366764BDBM50366764(MCL-117 | CHEMBL1790045)
Affinity DataKi:  0.00300nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430798BDBM50430798(CHEMBL2335120)
Affinity DataKi:  0.00372nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402777BDBM50402777(CHEMBL2208347)
Affinity DataKi:  0.00490nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402777BDBM50402777(CHEMBL2208347)
Affinity DataKi:  0.00560nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402776BDBM50402776(CHEMBL2208349)
Affinity DataKi:  0.00560nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402772BDBM50402772(CHEMBL2208350)
Affinity DataKi:  0.00710nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430801BDBM50430801(CHEMBL2334776)
Affinity DataKi:  0.00986nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142700BDBM50142700(CHEMBL326684)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180190BDBM50180190((1R,9R)-17-[(2S)-oxolan-2-ylmethyl]-17-azatetracyc...)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528967BDBM50528967(CHEMBL4439415)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528966BDBM50528966(CHEMBL4521879)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528965BDBM50528965(CHEMBL4550234)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528960BDBM50528960(CHEMBL4450250)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594821BDBM50594821(CHEMBL5175179)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430802BDBM50430802(CHEMBL2334775)
Affinity DataKi:  0.0128nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033535BDBM50033535(N-[(3R,4S)-1-((R)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi:  0.0130nMAssay Description:Binding affinity against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430803BDBM50430803(CHEMBL2334774)
Affinity DataKi:  0.0137nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594822BDBM50594822(CHEMBL5182849)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254566BDBM50254566(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  0.0150nMAssay Description:Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299217BDBM50299217((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.0160nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402773BDBM50402773(CHEMBL2208358)
Affinity DataKi:  0.0180nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 364562BDBM364562(US9862726, Compound 27 | N-((4bR,6S,8aS,9R)-11- (c...)
Affinity DataKi:  0.0190nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021347BDBM50021347(N-(3-Methyl-1-phenethyl-piperidin-4-yl)-N-phenyl-p...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402780BDBM50402780(CHEMBL2208348)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626414BDBM50626414(CHEMBL5431513)
Affinity DataKi:  0.0210nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012477BDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  0.0240nMAssay Description:Binding affinity against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303629BDBM50303629(17-(Cyclopropylmethyl)-N-(4-methoxyphenyl)morphina...)
Affinity DataKi:  0.0260nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142621BDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.0310nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594820BDBM50594820(CHEMBL5176887)
Affinity DataKi:  0.0320nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430799BDBM50430799(CHEMBL2334772)
Affinity DataKi:  0.0322nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469380BDBM50469380(CHEMBL4276875)
Affinity DataKi:  0.0370nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430800BDBM50430800(CHEMBL2334773)
Affinity DataKi:  0.0405nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142620BDBM50142620(CHEMBL3758712)
Affinity DataKi:  0.0420nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045775BDBM50045775(3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-...)
Affinity DataKi:  0.0430nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250450BDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.0480nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nM ΔG°:  -14.0kcal/mole IC50: 58nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86936BDBM86936(NSC_24824635 | CAS_24824635 | 17-cyclopropylmethyl...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82555BDBM82555(CAS_4424 | NSC_4424 | Naloxonazine)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179904BDBM179904(US9133125, Table D, Compound 8 | US9656961, Exampl...)
Affinity DataKi:  0.0500nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008984BDBM50008984(N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionami...)
Affinity DataKi:  0.0510nMAssay Description:Binding affinity to mu-opioid receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Alkermes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594825BDBM50594825(CHEMBL5198856)
Affinity DataKi:  0.0511nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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