Compile Data Set for Download or QSAR
Report error Found 2282 of ec50 for UniProtKB: Q99500
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23163BDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  0.100nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  0.134nMAssay Description:Agonist activity at human S1P3 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314403BDBM50314403((R)-2-amino-2-((R)-6-octyl-1,2,3,4-tetrahydronapht...)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human S1P3 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475576BDBM50475576(CHEMBL199791)
Affinity DataEC50:  0.178nMAssay Description:Binding potency at human S1P3 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  0.200nMAssay Description:Displacement of [33P]S1P from human recombinant S1P3 receptor expressed in HEK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314401BDBM50314401(2-amino-3-hydroxy-2-((R)-6-octyl-1,2,3,4-tetrahydr...)
Affinity DataEC50:  0.215nMAssay Description:Agonist activity at human S1P3 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314402BDBM50314402((R)-2-amino-2-((S)-6-octyl-1,2,3,4-tetrahydronapht...)
Affinity DataEC50:  0.286nMAssay Description:Agonist activity at human S1P3 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  0.449nMAssay Description:Agonist activity at human S1P3 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in HEK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  1.10nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 3 expressed in HEK293T cells using [gamma-35S]-GTP as radioligand (Experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50495961BDBM50495961(CHEMBL3121986)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells assessed as membrane-bound 35S-GTPgammaS incubated 30 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  1.20nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 3 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249263BDBM50249263((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propoxy)phenyla...)
Affinity DataEC50:  1.38nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23163BDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  1.40nMpH: 7.4Assay Description:Agonism of human S1P-3 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]GTP-gamma-S as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165403BDBM50165403(CHEMBL3799355)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  1.60nMAssay Description:Activity at human recombinant S1P3 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23164BDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  1.70nMAssay Description:Activity at human recombinant S1P3 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHOK1 cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23163BDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 3 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHOK1 cell membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496231BDBM50496231(CHEMBL3126589)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23164BDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at SIP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158336BDBM50158336(FINGOLIMOD HYDROCHLORIDE | 2-amino-2-(4-octylphene...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at S1P3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  3.10nMpH: 7.4Assay Description:Agonism of human S1P-3 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]GTP-gamma-S as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human S1P3R expressed in CHO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165404BDBM50165404(CHEMBL3800604)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23163BDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human S1P3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23163BDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at recombinant human S1P3 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496249BDBM50496249(CHEMBL3126587)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human recombinant S1P3 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at human S1P3R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315813BDBM50315813(2-Amino-4-(4'-benzyloxy-2'-fluorobiphenyl-4-yl)-2-...)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315816BDBM50315816(2-Amino-4-(2'-fluoro-4'-phenylthiobiphenyl-4-yl)-2...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496220BDBM50496220(CHEMBL3126588)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475575BDBM50475575(CHEMBL199754)
Affinity DataEC50:  5nMAssay Description:Binding potency at human S1P3 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human S1P3 receptor expressed in RBL cells by [35S]GTP-gammaS accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23165BDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human S1P3 receptor expressed in RBL cells assessed as [35S]GTPgammaS binding after 3 hrs by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313499BDBM50313499((S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutyl ...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50495973BDBM50495973(CHEMBL3121961)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells assessed as membrane-bound 35S-GTPgammaS incubated 30 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50475577BDBM50475577(CHEMBL382739)
Affinity DataEC50:  6.30nMAssay Description:Binding potency at human S1P3 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165405BDBM50165405(CHEMBL3799888)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  8.70nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 3 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  8.70nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 3 expressed in HEK293T cells using [gamma-35S]-GTP as radioligand (Experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50495977BDBM50495977(CHEMBL3122001)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells assessed as membrane-bound 35S-GTPgammaS incubated 30 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277185BDBM50277185((S)-2-amino-3-(2-fluoro-4-(octyloxy)phenylamino)-2...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277149BDBM50277149((S)-2-amino-3-(3-fluoro-4-(octyloxy)phenylamino)-2...)
Affinity DataEC50:  10.1nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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