Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 4107 for UniProtKB: P09917
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446681(CHEMBL3113617)
Affinity DataKi:  8.40nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446686(CHEMBL3113612)
Affinity DataKi:  9.5nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446680(CHEMBL3113618)
Affinity DataKi:  9.90nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446685(CHEMBL3113613)
Affinity DataKi:  37nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446678(CHEMBL3113620)
Affinity DataKi:  95nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50006819(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-aceta...)
Affinity DataKi:  100nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase in human cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446682(CHEMBL3113616)
Affinity DataKi:  320nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446677(CHEMBL3113621)
Affinity DataKi:  510nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446683(CHEMBL3113615)
Affinity DataKi:  820nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446679(CHEMBL3113619)
Affinity DataKi:  2.53E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446684(CHEMBL3113614)
Affinity DataKi:  4.16E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM86691(K604)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM86693(K376)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM86692(K117)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50444319(CHEMBL3094153)
Affinity DataKi:  7.03E+4nMAssay Description:Binding affinity to human 5-LOX using linoleic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50444319(CHEMBL3094153)
Affinity DataKi:  1.40E+5nMAssay Description:Binding affinity to human 5-LOX-linoleic acid complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182303(6-(3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182306(7-(3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50610906(CHEMBL5267320)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of 5-LOX (unknown origin) by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50610905(CHEMBL5267685)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of 5-LOX (unknown origin) by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50610907(CHEMBL5270325)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 5-LOX (unknown origin) by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182308(7-(3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182304(7-((3-fluoro-5-(3-hydroxypentan-3-yl)phenoxy)methy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50029559(2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182302(7-((3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypr...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182300(7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182305(7-((3-fluoro-5-(1-hydroxy-1-(thiazol-2-yl)propyl)p...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  3nMAssay Description:The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50045643(3-[1-(4-Chloro-benzyl)-4-methyl-6-(quinolin-2-ylme...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50045673(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182307(7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182298(7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182299(7-((3-fluoro-5-(1-hydroxy-1-(pyridin-2-yl)propyl)p...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50004424(CHEMBL3238463)
Affinity DataIC50:  4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182301(4-(4-chlorophenyl)-7-(3-fluoro-5-(1,1,1,3,3,3-hexa...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50004425(CHEMBL3238207)
Affinity DataIC50:  6nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50016991(7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  7nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50085160(CHEMBL32842 | L-674636 | {4-(4-Chloro-phenyl)-1-[4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50331806(CHEMBL1290649 | methyl 3-phenyl-6-((4-(1,1,1-trifl...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50409117(CHEMBL2093045)
Affinity DataIC50:  8nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446686(CHEMBL3113612)
Affinity DataIC50:  8nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIA in presence of pig liver esteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  8nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446681(CHEMBL3113617)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50182308(7-(3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human 5-LOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50085202(2-{4-(4-Fluoro-phenyl)-1-[4-(quinolin-2-ylmethoxy)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446686(CHEMBL3113612)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50031153(CHEMBL129970 | [1-{4-[4-((S)-2,2,4-Trimethyl-[1,3]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of LT biosynthesis in vitro using A-23,187-stimulated human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50000845(4-Methoxy-4-[3-(naphthalen-2-ylmethoxy)-phenyl]-te...)
Affinity DataIC50:  10nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 4107 total ) | Next | Last >>
Jump to: