Compile Data Set for Download or QSAR
Found 2756 of ic50 for UniProtKB: Q01959
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(CHEMBL343369 | Rhenium complex of 3-(2-Bromo-2,2,2...)
Affinity DataIC50:  0.146nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067771(3-(2-Methylsulfanyl-ethylsulfanyl)-propionic acid ...)
Affinity DataIC50:  0.227nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260904((1R,2R,3S,5S)-2-(2,2-dibromovinyl)-8-methyl-3-p-to...)
Affinity DataIC50:  0.230nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50102589(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260905((1R,2R,3S,5S)-3-(4-chlorophenyl)-2-(2,2-dibromovin...)
Affinity DataIC50:  0.320nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50:  0.360nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50:  0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  0.400nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50090975(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of dopamine (DA) reuptake using cloned human dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50046734(3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]octane...)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM160629(US9045468, 45)
Affinity DataIC50:  0.700nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of [125I]RTI-55 from recombinant human DAT expressed in CHOK1 cells after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50349803(CHEMBL1812741)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as inhibition of [3H]DA reuptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50102564(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM375641(US9908897, Example 21)
Affinity DataIC50:  0.776nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260933(3beta-(4-Methylphenyl)-2beta-(phenylethynyl)tropan...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260934(3beta-(4-Chlorophenyl)-2beta-(phenylethynyl)tropan...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50273607((1R,2S,3S,5R)-methyl 3-(4-chloro-3-methylphenyl)-8...)
Affinity DataIC50:  0.820nMAssay Description:Displacement of [3H]WIN35,428 from DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50349805(CHEMBL1812739)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as inhibition of [3H]DA reuptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM376888(4-(aminomethyl)-1-[2,3-difluoro-5-(3-fluorophenoxy...)
Affinity DataIC50:  0.891nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50177110(2-beta-(4-fluorophenyl)-3-beta-(4-methylphenyl)tro...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260935(3beta-(4-Chlorophenyl)-2beta-(4-nitrophenylethynyl...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM376885(4-(aminomethyl)-1-[2,5-difluoro-3-(3-fluorophenoxy...)
Affinity DataIC50:  0.912nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50:  0.990nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50:  0.990nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337915((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-3-methy...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM433654(US10562878, Compound 115)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM433711(US10562878, Compound 268 | US10562878, Compound 26...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM433734(US10562878, Compound 206 E1 | US10562878, Compound...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337830(CHEMBL1683875 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337830(CHEMBL1683875 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50337818(CHEMBL1683876 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50118266(9-Benzo[1,3]dioxol-5-yl-1,2,3,9-tetrahydro-4,9a-di...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of [3H]WIN-35428 radioligand binding to the Dopamine Transporter in guinea pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-3-(3,4-Dichloro-phenyl)-2-methoxycarbonyl-...)
Affinity DataIC50:  1.10nMAssay Description:Ability of the compound to inhibit human dopamine uptake by the human dopamine transporter in EM4 cells stably infected with Flag HA-hDATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut f£r Bioanorganische und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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