Compile Data Set for Download or QSAR
Report error Found 23 of kd for UniProtKB: P23975
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKd:  0.830nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50176062(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
Affinity DataKd:  1.40nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)
Affinity DataKd:  2nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM22417(LY 94939 | Nisoxetine Inhibitor | Nisoxetine | LY1...)
Affinity DataKd:  5.10nMAssay Description:Binding affinity to human wild type NET expressed in african green monkey COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069448((1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-...)
Affinity DataKd:  21nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069449((2R,3R)-1-Dimethylamino-4,4-dimethyl-2-naphthalen-...)
Affinity DataKd:  30nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKd:  40nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50459929(CHEMBL4228171)
Affinity DataKd:  42nMAssay Description:Binding affinity to human NET expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069453((1R,2R)-3-Dimethylamino-2-naphthalen-2-yl-1-phenyl...)
Affinity DataKd:  44nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069442((2R,3R)-1-Amino-4,4-dimethyl-2-naphthalen-2-yl-pen...)
Affinity DataKd:  55nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine(viloxazine) ...)
Affinity DataKd:  155nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKd:  240nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069447(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Affinity DataKd:  360nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50028094((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataKd:  420nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataKd:  1.06E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKd:  1.54E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069446((1S,2R)-1-Cyclohexyl-3-dimethylamino-2-(4-methoxy-...)
Affinity DataKd:  1.80E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069445((1R,2R)-3-Dimethylamino-1,2-diphenyl-propan-1-ol; ...)
Affinity DataKd:  2.25E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069450((2R,3R)-1-Dimethylamino-4,4-dimethyl-2-phenyl-pent...)
Affinity DataKd:  3.43E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069443((1R,2R)-3-Amino-1,2-diphenyl-propan-1-ol; hydrochl...)
Affinity DataKd:  1.25E+4nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069444((1R,2R)-3-Amino-2-phenyl-1-(2,4,6-trimethyl-phenyl...)
Affinity DataKd:  2.25E+4nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069452((1R,2R)-3-Dimethylamino-2-phenyl-1-(2,4,6-trimethy...)
Affinity DataKd:  3.58E+4nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069451((2R,3R)-1-Amino-4,4-dimethyl-2-phenyl-pentan-3-ol;...)
Affinity DataKd:  4.79E+4nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed