Compile Data Set for Download or QSAR
maximum 50k data
Found 1374 of ic50 for UniProtKB: P04585
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM168608(US9079834, 2)
Affinity DataIC50:  0.0190nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM60467(BDBM168607 | US9079834, 1-1)
Affinity DataIC50:  0.0300nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180212(US9133157, 94)
Affinity DataIC50:  0.0900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM60623(BDBM180165 | US9133157, 103)
Affinity DataIC50:  0.0900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180171(US9133157, 53)
Affinity DataIC50:  0.156nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180183(US9133157, 65)
Affinity DataIC50:  0.180nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180163(US9133157, 44)
Affinity DataIC50:  0.196nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180201(US9133157, 83)
Affinity DataIC50:  0.300nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180164(US9133157, 102 | US9133157, 45)
Affinity DataIC50:  0.308nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180211(US9133157, 93)
Affinity DataIC50:  0.310nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180119(US9133157, 8)
Affinity DataIC50:  0.310nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180206(US9133157, 88)
Affinity DataIC50:  0.330nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180203(US9133157, 85)
Affinity DataIC50:  0.330nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180204(US9133157, 86)
Affinity DataIC50:  0.340nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM168610(US9079834, 5)
Affinity DataIC50:  0.390nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461442(CHEMBL4225363)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461431(CHEMBL4228517)
Affinity DataIC50:  0.420nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM168612(US9079834, 7)
Affinity DataIC50:  0.430nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180216(US9133157, 98)
Affinity DataIC50:  0.440nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180135(US9133157, 16)
Affinity DataIC50:  0.440nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180192(US9133157, 74)
Affinity DataIC50:  0.450nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180232(US9133157, 117)
Affinity DataIC50:  0.470nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180116(US9133157, 5)
Affinity DataIC50:  0.540nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM168609(US9079834, 4)
Affinity DataIC50:  0.590nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180164(US9133157, 102 | US9133157, 45)
Affinity DataIC50:  0.630nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180120(US9133157, 9)
Affinity DataIC50:  0.630nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180202(US9133157, 84)
Affinity DataIC50:  0.75nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180229(US9133157, 114)
Affinity DataIC50:  0.770nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180219(US9133157, 101)
Affinity DataIC50:  0.840nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180222(US9133157, 104)
Affinity DataIC50:  0.850nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180218(US9133157, 100)
Affinity DataIC50:  0.900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461430(CHEMBL4226862)
Affinity DataIC50:  1nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180215(US9133157, 97)
Affinity DataIC50:  1.23nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461417(CHEMBL4225028)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180175(US9133157, 57)
Affinity DataIC50:  1.32nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180147(US9133157, 28)
Affinity DataIC50:  1.45nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461438(CHEMBL4226921)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180130(US9133157, 11)
Affinity DataIC50:  1.61nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461421(CHEMBL3828596)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180223(US9133157, 105)
Affinity DataIC50:  1.77nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27595(2-{4-[3-chloro-4-(2-{[5-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50:  1.90nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27583(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50:  1.90nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180214(US9133157, 96)
Affinity DataIC50:  1.95nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM25330(2-[4-(dimethylamino)oxan-4-yl]-N-[(4-fluorophenyl)...)
Affinity DataIC50:  2nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM50461435(CHEMBL4224769)
Affinity DataIC50:  2nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27599(2-{4-[3-chloro-4-(2-{[4-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180170(US9133157, 52)
Affinity DataIC50:  2nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180178(US9133157, 60)
Affinity DataIC50:  2.01nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180191(US9133157, 73)
Affinity DataIC50:  2.03nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Canada

US Patent
LigandPNGBDBM180151(US9133157, 32)
Affinity DataIC50:  2.27nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In DepthDetails US Patent
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