Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 45 of kd for UniProtKB: P18031
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50518208(CHEMBL4592897)
Affinity DataKd:  8.40nMAssay Description:Binding affinity to recombinant human N-terminal poly histidine-tagged PTP1B (Glu2 to Asn321 residues) expressed in Escherichia coli by surface plasm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557904(CHEMBL4782991)
Affinity DataKd:  15.1nMAssay Description:Binding affinity to recombinant human PTP1B measured by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50518206(CHEMBL4557598)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant human N-terminal poly histidine-tagged PTP1B (Glu2 to Asn321 residues) expressed in Escherichia coli by surface plasm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557999(CHEMBL4786214)
Affinity DataKd:  50nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557998(CHEMBL4796866)
Affinity DataKd:  50nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557905(CHEMBL4789031)
Affinity DataKd:  60.7nMAssay Description:Binding affinity to recombinant human PTP1B measured by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557903(CHEMBL4748920)
Affinity DataKd:  77.8nMAssay Description:Binding affinity to recombinant human PTP1B measured by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557906(CHEMBL4789297)
Affinity DataKd:  86.3nMAssay Description:Binding affinity to recombinant human PTP1B measured by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557990(CHEMBL4752726)
Affinity DataKd:  90nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557991(CHEMBL4754600)
Affinity DataKd:  90nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557992(CHEMBL4762078)
Affinity DataKd:  100nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557993(CHEMBL4740579)
Affinity DataKd:  100nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557902(CHEMBL4790195)
Affinity DataKd:  105nMAssay Description:Binding affinity to recombinant human PTP1B measured by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557983(CHEMBL4793211)
Affinity DataKd:  110nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557982(CHEMBL4762824)
Affinity DataKd:  110nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557987(CHEMBL4777832)
Affinity DataKd:  120nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557986(CHEMBL4746426)
Affinity DataKd:  120nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50518207(CHEMBL4446033)
Affinity DataKd:  128nMAssay Description:Binding affinity to recombinant human N-terminal poly histidine-tagged PTP1B (Glu2 to Asn321 residues) expressed in Escherichia coli by surface plasm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557988(CHEMBL4786891)
Affinity DataKd:  210nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557989(CHEMBL4779255)
Affinity DataKd:  210nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557980(CHEMBL4741877)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557981(CHEMBL4796812)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557985(CHEMBL4759705)
Affinity DataKd:  240nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557984(CHEMBL4744734)
Affinity DataKd:  240nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557997(CHEMBL4786563)
Affinity DataKd:  270nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557996(CHEMBL4778692)
Affinity DataKd:  270nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557995(CHEMBL4800222)
Affinity DataKd:  290nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557994(CHEMBL4793855)
Affinity DataKd:  290nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+3nMAssay Description:Dissociation constant of the compound against protein tyrosine phosphatase PTB1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataKd:  2.23E+3nMAssay Description:Binding affinity to human PTP1B (1 to 321 residues) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataKd:  6.08E+3nMAssay Description:Binding affinity to human N-terminal His6-tagged PTP1B catalytic domain (1 to 298 residues) expressed in Escherichia coli strain Rosetta2 (DE3) by sw...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50098803(CHEMBL3329937)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKd:  2.60E+4nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM13951(2-[(2,3-Dimethylphenyl)oxalylamino]benzoic acid | ...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM13951(2-[(2,3-Dimethylphenyl)oxalylamino]benzoic acid | ...)
Affinity DataKd:  1.00E+5nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant of the compound against Protein-tyrosine phosphatase 1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50131549(4-Amino-3-bromo-5-cyano-2-hydroxy-benzoic acid | C...)
Affinity DataKd:  9.10E+5nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50546252(CHEBI:18386 | QUINALDIC ACID | Quinoline-2-Carboxy...)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50149218(Benzo[b]thiophene-2-carboxylic acid | CHEMBL312607)
Affinity DataKd: >1.00E+6nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50131554(5-Hydroxy-6,8-dimethyl-quinoline-2-carboxylic acid...)
Affinity DataKd:  1.56E+7nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed