Compile Data Set for Download or QSAR
Found 29 of ki for UniProtKB: Q8NEB9
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571463(CHEMBL4862803)
Show SMILES O=c1cc(cc([nH]1)N1C[C@@H]2C[C@@H]2[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  4nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571474(CHEMBL4857803)
Show SMILES O=c1cc(nc([nH]1)N1C[C@@H]2C[C@@H]2[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  5nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400)
Show SMILES C[C@@H]1CCN([C@H]1Cc1ccccc1)c1nc(cc(=O)[nH]1)N1CCOCC1
Affinity DataKi:  6nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571467(CHEMBL4850755)
Show SMILES O=c1cc(nc([nH]1)N1CCCCC[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  8nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571455(CHEMBL4873212)
Show SMILES O=c1cc(cc([nH]1)N1CCC[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  9nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(=O)cc(o1)N1CCOCC1
Show InChI InChI=1S/C23H21NO4S/c1-26-18-5-6-21-16(12-18)11-15-3-2-4-19(23(15)29-21)20-13-17(25)14-22(28-20)24-7-9-27-10-8-24/h2-6,12-14H,7-11H2,1H3
Affinity DataKi:  15nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571466(CHEMBL4878312)
Show SMILES Oc1cc(nc(n1)N1CCC[C@@H]1Cc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C19H24N4O2/c24-18-14-17(22-9-11-25-12-10-22)20-19(21-18)23-8-4-7-16(23)13-15-5-2-1-3-6-15/h1-3,5-6,14,16H,4,7-13H2,(H,20,21,24)/t16-/m1/s1
Affinity DataKi:  16nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571471(CHEMBL4858310)
Show SMILES O=c1cc(nc([nH]1)N1C[C@H]2C[C@H]2[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  21nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50343200(CHEMBL1615189 | N-(6-(6-Chloro-5-(4-fluorophenylsu...)
Show SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1
Show InChI InChI=1S/C20H14ClFN4O3S2/c1-11(27)24-20-25-16-7-2-12(9-18(16)30-20)13-8-17(19(21)23-10-13)26-31(28,29)15-5-3-14(22)4-6-15/h2-10,26H,1H3,(H,24,25,27)
Affinity DataKi:  31nMAssay Description:Inhibition of human VPS34 after 30 mins by fluorescence-based immunoassayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571452(CHEMBL4874992)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(O)nc(n1)N1CCOCC1
Show InChI InChI=1S/C22H21N3O3S/c1-27-16-5-6-19-15(12-16)11-14-3-2-4-17(21(14)29-19)18-13-20(26)24-22(23-18)25-7-9-28-10-8-25/h2-6,12-13H,7-11H2,1H3,(H,23,24,26)
Affinity DataKi:  35nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571460(CHEMBL4858974)
Show SMILES FC1(F)CCN([C@H]1Cc1ccccc1)c1cc(cc(=O)[nH]1)N1CCOCC1
Affinity DataKi:  39nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571454(CHEMBL4873551)
Show SMILES O=c1cc(cc([nH]1)N1CCCC1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  49nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)
Show SMILES O=c1cc(cc([nH]1)N1CCCCC[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  50nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640)
Show SMILES O=c1cc(cc([nH]1)N1C[C@H]2C[C@H]2[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  98nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571461(CHEMBL4866506)
Show SMILES F[C@@H]1CCN([C@H]1Cc1ccccc1)c1cc(cc(=O)[nH]1)N1CCOCC1
Affinity DataKi:  110nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571446(CHEMBL4879094)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(cc(=O)[nH]1)N1CCOCC1
Show InChI InChI=1S/C23H22N2O3S/c1-27-18-5-6-21-16(12-18)11-15-3-2-4-19(23(15)29-21)20-13-17(14-22(26)24-20)25-7-9-28-10-8-25/h2-6,12-14H,7-11H2,1H3,(H,24,26)
Affinity DataKi:  130nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571458(CHEMBL4846084)
Show SMILES O=c1cc(cc([nH]1)N1CCCC[C@@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  170nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571465(CHEMBL4852165)
Show SMILES Oc1cc(nc(n1)N1CCOCC1)N1CCC[C@@H]1Cc1ccccc1
Show InChI InChI=1S/C19H24N4O2/c24-18-14-17(20-19(21-18)22-9-11-25-12-10-22)23-8-4-7-16(23)13-15-5-2-1-3-6-15/h1-3,5-6,14,16H,4,7-13H2,(H,20,21,24)/t16-/m1/s1
Affinity DataKi:  270nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571456(CHEMBL4851518)
Show SMILES O=c1cc(cc([nH]1)N1CCC[C@H]1Cc1ccccc1)N1CCOCC1
Affinity DataKi:  630nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571473(CHEMBL4856420)
Show SMILES C[C@@H]1CN(CCO1)c1cc([nH]c(=O)c1)N1C[C@@H]2C[C@@H]2[C@@H]1Cc1ccccc1
Affinity DataKi:  750nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571469(CHEMBL4852763)
Show SMILES C[C@@H]1CN(CCO1)c1cc(=O)[nH]c(n1)N1CCCCC[C@@H]1Cc1ccccc1
Affinity DataKi:  840nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571472(CHEMBL4867495)
Show SMILES C[C@@H]1CN(CCO1)c1cc(=O)[nH]c(n1)N1C[C@H]2C[C@H]2[C@@H]1Cc1ccccc1
Affinity DataKi:  880nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571447(CHEMBL4872413)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(cc(=O)n1C)N1CCOCC1
Show InChI InChI=1S/C24H24N2O3S/c1-25-21(14-18(15-23(25)27)26-8-10-29-11-9-26)20-5-3-4-16-12-17-13-19(28-2)6-7-22(17)30-24(16)20/h3-7,13-15H,8-12H2,1-2H3
Affinity DataKi:  910nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571475(CHEMBL4853948)
Show SMILES C[C@@H]1CN(CCO1)c1cc(=O)[nH]c(n1)N1C[C@@H]2C[C@@H]2[C@@H]1Cc1ccccc1
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571468(CHEMBL4845919)
Show SMILES C[C@@H]1CN(CCO1)c1cc([nH]c(=O)c1)N1CCCCC[C@@H]1Cc1ccccc1
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571453(CHEMBL4868624)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(nc(O)n1)N1CCOCC1
Show InChI InChI=1S/C22H21N3O3S/c1-27-16-5-6-19-15(12-16)11-14-3-2-4-17(21(14)29-19)18-13-20(24-22(26)23-18)25-7-9-28-10-8-25/h2-6,12-13H,7-11H2,1H3,(H,23,24,26)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571450(CHEMBL4850102)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(cc(OC)n1)N1CCOCC1
Show InChI InChI=1S/C24H24N2O3S/c1-27-19-6-7-22-17(13-19)12-16-4-3-5-20(24(16)30-22)21-14-18(15-23(25-21)28-2)26-8-10-29-11-9-26/h3-7,13-15H,8-12H2,1-2H3
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571470(CHEMBL4869283)
Show SMILES C[C@@H]1CN(CCO1)c1cc([nH]c(=O)c1)N1C[C@H]2C[C@H]2[C@@H]1Cc1ccccc1
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50571451(CHEMBL4851148)
Show SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1nc(O)cc(n1)N1CCOCC1
Show InChI InChI=1S/C22H21N3O3S/c1-27-16-5-6-18-15(12-16)11-14-3-2-4-17(21(14)29-18)22-23-19(13-20(26)24-22)25-7-9-28-10-8-25/h2-6,12-13H,7-11H2,1H3,(H,23,24,26)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid