TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human carbonic anhydrase 3More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human carbonic anhydrase 3More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 146nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
Affinity DataKi: 240nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 254nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydrase (Competitive)More data for this Ligand-Target Pair
Affinity DataKi: 374nMAssay Description:Inhibition of human recombinant CA3 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 437nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 443nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 510nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 528nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 3 + BH(Homo sapiens (Human))
University Of Tampere And Tampere University Hospital
University Of Tampere And Tampere University Hospital
Affinity DataKi: 534nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 3 + BH(Homo sapiens (Human))
University Of Tampere And Tampere University Hospital
University Of Tampere And Tampere University Hospital
Affinity DataKi: 537nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 584nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 710nM ΔG°: -8.38kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 710nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 760nM ΔG°: -8.34kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 877nM ΔG°: -8.20kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 988nMAssay Description:Inhibition of human recombinant CA3 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.13E+3nM ΔG°: -8.05kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.21E+3nM ΔG°: -8.01kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nM ΔG°: -7.59kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.58E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.57E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.58E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.62E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of human carbonic anhydrase 3More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.91E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair