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Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172414(2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074200(3-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-5-[...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 0.501nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060426(Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060426(Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060426(Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]5-HT binding displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074205(N-(3-{4-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-p...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074165(3-[2-((S)-2-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50077807(3-{3-[4-Fluoro-4-(2-fluoro-benzyl)-piperidin-1-yl]...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083105(Pyridin-2-yl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074163(3-(2-Azetidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H...)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50077830(3-{3-[4-Fluoro-4-(3-fluoro-benzyl)-piperidin-1-yl]...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083131(1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074195(3-(3-Morpholin-4-yl-propyl)-5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083111(N-{4-[(R)-1-({1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol...)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083142(N-{4-[({1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)...)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50212607(CHEMBL57330)
Affinity DataIC50: 9nMAssay Description:The compound was evaluated for its ability to displace [3H]5-HT from 5-hydroxytryptamine 1B receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails

Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083108(N-{4-[(S)-1-({1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol...)
Affinity DataIC50: 9.30nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074194(2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50473512(CHEMBL2368254)
Affinity DataIC50: 9.5nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 10nMAssay Description:Binding affinity at cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells by [3H]5-HT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083091(N-Methyl-N-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074147(N-Benzyl-N-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-ind...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 11nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-5-HT from human 5HT-1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 5HT1B expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074177(Furan-3-ylmethyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50455556(CHEMBL2114040)
Affinity DataIC50: 13nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074192(3-[3-(4-Phenyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074199(3-{3-[4-(1-Phenyl-ethyl)-piperazin-1-yl]-propyl}-5...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083090((R)-N*2*,N*2*-Dimethyl-1-phenyl-N*1*-{1-[3-(5-[1,2...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50077814(3-{3-[4-Fluoro-4-(2-trifluoromethyl-benzyl)-piperi...)
Affinity DataIC50: 14nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50083112(((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50473521(CP-122288 | CHEMBL159332)
Affinity DataIC50: 14nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060431(3-(3-Piperidin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: 15nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]5-HT binding displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50060431(3-(3-Piperidin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074154(Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50065417(3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-...)
Affinity DataIC50: 15nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50065417(3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]-5-HT from human 5HT-1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50065417(3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human 5HT1B expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 16nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]5-HT binding displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50077820(3-(3-{4-Fluoro-4-[2-(2-fluoro-phenyl)-ethyl]-piper...)
Affinity DataIC50: 16nMAssay Description:Displacement of specific [3H]5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50074184(Methyl-(2-phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H...)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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