Affinity DataKi: 0.0300nMAssay Description:The new compounds have been tested by radioligand binding competition activity at the human 5-HT1A (FAST-0500B), 5-HT2A (FAST-0505B), 5-HT2Cedited (F...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:The new compounds have been tested by radioligand binding competition activity at the human 5-HT1A (FAST-0500B), 5-HT2A (FAST-0505B), 5-HT2Cedited (F...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.153nMAssay Description:Displacement of [3H]lysergic acid from 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.153nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:The new compounds have been tested by radioligand binding competition activity at the human 5-HT1A (FAST-0500B), 5-HT2A (FAST-0505B), 5-HT2Cedited (F...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Compound was evaluated for binding affinity against human cloned 5-hydroxytryptamine 7 receptor in HEK 293 cells using [3H]5-CT as the radioligand (n...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand bind...More data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Binding affinity against 5-hydroxytryptamine 7 human receptorsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 7.4Assay Description:Binding experiments were conducted in 96-well microplates in a total volume of 250 μL of buffer (50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 1 mM EDTA)....More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against 5-Hydroxy tryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
