Compile Data Set for Download or QSAR
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Report error Found 3016 of affinity data for UniProtKB/TrEMBL: O00519
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166868(CHEMBL3797635)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166873(CHEMBL3800456)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166871(CHEMBL3797841)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166866(CHEMBL3798156)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166869(CHEMBL3799744)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166866(CHEMBL3798156)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166890(CHEMBL3797809)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166867(CHEMBL3798476)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166867(CHEMBL3798476)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166910(CHEMBL3798355)
Affinity DataKi:  0.0150nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166911(CHEMBL3799516)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166878(CHEMBL3800599)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166891(CHEMBL3799008)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166870(CHEMBL3797226)
Affinity DataKi:  0.0340nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166875(CHEMBL3797377)
Affinity DataKi:  0.0380nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166877(CHEMBL3798594)
Affinity DataKi:  0.0560nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166877(CHEMBL3798594)
Affinity DataKi:  0.0560nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.0940nMAssay Description:Binding affinity for human fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166889(CHEMBL3799633)
Affinity DataKi:  0.147nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant FAAH expressed COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161512(7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  0.290nMpH: 9.0Assay Description:Inhibition of FAAH (unknown origin) at pH 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50275119(1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50275119(1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23069(3-[4-(benzyloxy)phenyl]-1-[5-(pyridin-2-yl)-1,3-ox...)
Affinity DataKi:  0.450nM ΔG°:  -53.3kJ/moleT: 25°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50342116((S)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50372374(CHEMBL258820)
Affinity DataKi:  0.510nMAssay Description:Inhibition of human recombinant FAAH expressed COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50350547(CHEMBL257307)
Affinity DataKi:  0.570nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204478(1-(5-(4-methylpyridin-2-yl)oxazol-2-yl)-7-phenylhe...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23079(3-[4-(benzyloxy)phenyl]-1-{pyrido[2,3-d][1,3]oxazo...)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/moleT: 25°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50372399(CHEMBL405604)
Affinity DataKi:  0.670nMAssay Description:Inhibition of human recombinant FAAH expressed COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50350545(CHEMBL257305)
Affinity DataKi:  0.690nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23078(3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50350546(CHEMBL1812708)
Affinity DataKi:  0.75nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM23078(3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Affinity DataKi:  0.75nMpH: 9.0Assay Description:Inhibition of FAAH (unknown origin) at pH 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204510(1-(5-(4-methoxypyridin-2-yl)oxazol-2-yl)-7-phenylh...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204483(7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50204483(7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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