Compile Data Set for Download or QSAR
maximum 50k data
Found 96 of ic50 for UniProtKB: Q16552
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582230(CHEMBL5091495)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578383(CHEMBL4870813)
Affinity DataIC50:  1nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582232(CHEMBL5091603)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582229(CHEMBL5080633)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582227(CHEMBL5081660)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582231(CHEMBL5092697)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582228(CHEMBL5077953)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578382(CHEMBL4865978)
Affinity DataIC50:  2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578381(CHEMBL4860574)
Affinity DataIC50:  2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578386(CHEMBL4872143)
Affinity DataIC50:  2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574356(CHEMBL4845695)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578385(CHEMBL4851738)
Affinity DataIC50:  3nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578384(CHEMBL4850368)
Affinity DataIC50:  3nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574357(CHEMBL4855085)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574355(CHEMBL4874078)
Affinity DataIC50:  7nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50581144(CHEMBL5087050)
Affinity DataIC50:  9nMAssay Description:Inhibition of IL-17A (unknown origin) measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574354(CHEMBL4866932)
Affinity DataIC50:  10nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574352(CHEMBL4876088)
Affinity DataIC50:  10nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574353(CHEMBL4860250)
Affinity DataIC50:  14nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573258(CHEMBL4869568)
Affinity DataIC50:  70nMAssay Description:Binding affinity to biotinylated human IL-17A assessed as inhibition of IL-17A interaction with 1L-17RA by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419139(BDBM50461078 | N-(4-ethylphenyl)-N- isobutyl-3- me...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419214(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50581142(CHEMBL3785600)
Affinity DataIC50: <100nMAssay Description:Inhibition of IL-17A (unknown origin) by ELISA IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50581141(CHEMBL5075374)
Affinity DataIC50: <100nMAssay Description:Inhibition of IL-17A (unknown origin) by ELISA IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419256(N-(2,4-dimethylphenyl)-N- isobutyl-3-(S- methylsul...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461065(CHEMBL4225020 | US10457637, Compound 18)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419154(N-(4-ethylphenyl)-N- isobutyl-3-methanesulfinyl- 4...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419155(N-(4-ethylphenyl)-N- isobutyl-3-methanesulfinyl- 4...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419252(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419157(N-(4-ethylphenyl)-3- hydroxymethyl-N-isobutyl- 4-(...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461076(CHEMBL4227214 | US10457637, Compound 124)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461068(CHEMBL4228069 | US10457637, Compound 24)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419242(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419162(N-(4-ethylphenyl)-4-((4- fluorotetrahydro-2H-pyran...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461074(CHEMBL4227729 | US10457637, Compound 52)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461066(CHEMBL4228566 | US10457637, Compound 53)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461075(CHEMBL4225072 | US10457637, Compound 55)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419234(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419189(N-(4-ethylphenyl)-4-(((3- hydroxycyclobutyl)methyl...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419225(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419192(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419218(4-((((1R,5S,6S)-3- oxabicyclo[3.1.0]hexan-6- yl)me...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50461069(CHEMBL4228522 | US10457637, Compound 66)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419139(BDBM50461078 | N-(4-ethylphenyl)-N- isobutyl-3- me...)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50581145(CHEMBL5079201)
Affinity DataIC50:  160nMAssay Description:Inhibition of IL-17A (unknown origin) measured by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50581146(CHEMBL5069442)
Affinity DataIC50:  190nMAssay Description:Inhibition of IL-17A (unknown origin) measured by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419196(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM419222(4-(((2-oxaspiro[3.3]heptan- 6-yl)methyl)amino)-N-(...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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