Compile Data Set for Download or QSAR
Report error Found 80 of ki for UniProtKB: P78527
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataKi:  0.650nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731587(US12269804, Compound 11)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731569(US12269804, Compound 16)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731586(US12269804, Compound 10)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731568(US12269804, Compound 15)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731585(US12269804, Compound 36)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731567(US12269804, Compound 14)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731584(US12269804, Compound 35)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731583(US12269804, Compound 34)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731582(US12269804, Compound 33)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731560(US12269804, Compound 5)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731590(US12269804, Compound 27)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731588(US12269804, Compound 12)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731578(US12269804, Compound 28)
Affinity DataKi:  2nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731593(US12269804, Compound 38)
Affinity DataKi:  2nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731557(US12269804, Compound 2)
Affinity DataKi:  2nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731591(US12269804, Compound 29)
Affinity DataKi:  2nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731589(US12269804, Compound 26)
Affinity DataKi:  2nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731561(US12269804, Compound 6)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731594(US12269804, Compound 39)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731559(US12269804, Compound 4)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731575(US12269804, Compound 24)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731574(US12269804, Compound 23)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731556(US12269804, Compound 1)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731571(US12269804, Compound 20)
Affinity DataKi:  3nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731570(US12269804, Compound 19)
Affinity DataKi:  4nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731579(US12269804, Compound 30)
Affinity DataKi:  4nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731592(US12269804, Compound 40)
Affinity DataKi:  4nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731581(US12269804, Compound 32)
Affinity DataKi:  5nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731580(US12269804, Compound 31)
Affinity DataKi:  5nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731577(US12269804, Compound 25)
Affinity DataKi:  5nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731558(US12269804, Compound 3)
Affinity DataKi:  5nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50341751(3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfon...)
Affinity DataKi:  6nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731572(US12269804, Compound 21)
Affinity DataKi:  6nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571473(CHEMBL4856420 | US11685734, Example 39)
Affinity DataKi:  7nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731562(US12269804, Compound 7)
Affinity DataKi:  8nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731573(US12269804, Compound 22)
Affinity DataKi:  8nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731566(US12269804, Compound 13)
Affinity DataKi:  15nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM731563(US12269804, Compound 8)
Affinity DataKi:  15nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50594892(CHEMBL5192303)
Affinity DataKi: <100nMAssay Description:Inhibition of DNA-PK (unknown origin) assessed as inhibition constant using Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys-Lys peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50594891(CHEMBL5171087)
Affinity DataKi: <100nMAssay Description:Inhibition of DNA-PK (unknown origin) assessed as inhibition constant using Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys-Lys peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400 | US11685734, Example 215)
Affinity DataKi:  110nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM15234(NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...)
Affinity DataKi:  120nMAssay Description:Binding affinity for DNA dependent protein kinase isolated from HeLa cells; Range is 20-120More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM15234(NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...)
Affinity DataKi:  120nMAssay Description:Inhibition of DNA-PK isolated from human HeLa cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)
Affinity DataKi:  160nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640 | US11685734, Example 43)
Affinity DataKi:  180nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50274538(CHEMBL4126773)
Affinity DataKi:  260nMAssay Description:Inhibition of DNA-PK (unknown origin) using EPPLSQEAFADLWKKK as substrate after 15 mins in presence of [33P-ATP] by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513172(CHEMBL4467848)
Affinity DataKi:  785nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50093352(CHEMBL3586678)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of DNAPK (unknown origin) using ATP and PPLSQEAFADLWKKK substrate by radiometric peptide assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513180(CHEMBL4593939)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 80 total ) | Next | Last >>
Jump to: