Compile Data Set for Download or QSAR
Found 4317 of ec50 for UniProtKB: P38532
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Show SMILES Cc1ccc(-c2nc(no2)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C15H11ClN2O/c1-10-7-8-12(13(16)9-10)15-17-14(18-19-15)11-5-3-2-4-6-11/h2-9H,1H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39066(2,6-diphenylimidazo[2,1-b][1,3,4]thiadiazole | MLS...)
Show SMILES c1c(nc2sc(nn12)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C16H11N3S/c1-3-7-12(8-4-1)14-11-19-16(17-14)20-15(18-19)13-9-5-2-6-10-13/h1-11H
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50238226(2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine...)
Show SMILES c1ccc(cc1)-c1ccc(cc1)-c1nc(no1)-c1ccccn1
Show InChI InChI=1S/C19H13N3O/c1-2-6-14(7-3-1)15-9-11-16(12-10-15)19-21-18(22-23-19)17-8-4-5-13-20-17/h1-13H
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62273(2,4-dimethylbenzoic acid [(Z)-[amino(2-pyridinyl)m...)
Show SMILES Cc1ccc(C(=O)ON=C(N)c2ccccn2)c(C)c1
Show InChI InChI=1S/C15H15N3O2/c1-10-6-7-12(11(2)9-10)15(19)20-18-14(16)13-5-3-4-8-17-13/h3-9H,1-2H3,(H2,16,18)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64310(Furan-2-carboxylic acid [5-(2,2-dimethyl-propionyl...)
Show SMILES CC(C)(C)C(=O)Nc1ccc(NC(=O)c2ccco2)nc1
Show InChI InChI=1S/C15H17N3O3/c1-15(2,3)14(20)17-10-6-7-12(16-9-10)18-13(19)11-5-4-8-21-11/h4-9H,1-3H3,(H,17,20)(H,16,18,19)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48210(2-[4-[(5-tert-butyl-2-furoyl)amino]phenyl]acetic a...)
Show SMILES CC(C)(C)c1ccc(o1)C(=O)Nc1ccc(CC(O)=O)cc1
Show InChI InChI=1S/C17H19NO4/c1-17(2,3)14-9-8-13(22-14)16(21)18-12-6-4-11(5-7-12)10-15(19)20/h4-9H,10H2,1-3H3,(H,18,21)(H,19,20)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48217(1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-4-phenyl-but...)
Show SMILES O=C(CCCc1ccccc1)c1ccc2OCCOc2c1
Show InChI InChI=1S/C18H18O3/c19-16(8-4-7-14-5-2-1-3-6-14)15-9-10-17-18(13-15)21-12-11-20-17/h1-3,5-6,9-10,13H,4,7-8,11-12H2
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62947(MLS000539987 | N,N-dimethylcarbamothioic acid O-[4...)
Show SMILES CN(C)C(=S)Oc1c(C)cc(cc1C)C(=O)CSc1ccc(F)cc1
Show InChI InChI=1S/C19H20FNO2S2/c1-12-9-14(10-13(2)18(12)23-19(24)21(3)4)17(22)11-25-16-7-5-15(20)6-8-16/h5-10H,11H2,1-4H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62958(MLS000531259 | N'-(4-hydroxy-3-methoxybenzylid...)
Show SMILES COc1cc(C=NN=C(Nc2ccc(C)cc2)c2nc3ccccc3s2)ccc1O
Show InChI InChI=1S/C23H20N4O2S/c1-15-7-10-17(11-8-15)25-22(23-26-18-5-3-4-6-21(18)30-23)27-24-14-16-9-12-19(28)20(13-16)29-2/h3-14,28H,1-2H3,(H,25,27)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48275(Acetic acid N-(2,4-dimethyl-phenyl)-N'-[3-oxo-...)
Show SMILES CC(=O)N(N=C1Sc2ccccc2C1=O)c1ccc(C)cc1C
Show InChI InChI=1S/C18H16N2O2S/c1-11-8-9-15(12(2)10-11)20(13(3)21)19-18-17(22)14-6-4-5-7-16(14)23-18/h4-10H,1-3H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62610(5-methyl-7-(4-methyl-1-piperidinyl)-3-phenylpyrazo...)
Show SMILES CC1CCN(CC1)c1cc(C)nc2c(cnn12)-c1ccccc1
Show InChI InChI=1S/C19H22N4/c1-14-8-10-22(11-9-14)18-12-15(2)21-19-17(13-20-23(18)19)16-6-4-3-5-7-16/h3-7,12-14H,8-11H2,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM40831((4-ethylpiperazino)methylene-(4,5,6,7-tetrahydro-1...)
Show SMILES CCN1CCN(CC1)C=Nc1nc2CCCCc2s1
Show InChI InChI=1S/C14H22N4S/c1-2-17-7-9-18(10-8-17)11-15-14-16-12-5-3-4-6-13(12)19-14/h11H,2-10H2,1H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64056(MLS001065900 | N-[4-(1,3-benzothiazol-2-yl)phenyl]...)
Show SMILES CN(C(=O)OC(C)(C)C)c1ccc(cc1)-c1nc2ccccc2s1
Show InChI InChI=1S/C19H20N2O2S/c1-19(2,3)23-18(22)21(4)14-11-9-13(10-12-14)17-20-15-7-5-6-8-16(15)24-17/h5-12H,1-4H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64076(4-[2-[(1-propan-2-yl-3-indolyl)methylidene]hydrazi...)
Show SMILES CC(C)n1cc(CN=Nc2ccc(cc2)C(O)=O)c2ccccc12
Show InChI InChI=1S/C19H19N3O2/c1-13(2)22-12-15(17-5-3-4-6-18(17)22)11-20-21-16-9-7-14(8-10-16)19(23)24/h3-10,12-13H,11H2,1-2H3,(H,23,24)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64082(2-[2-(1-hydroxycyclohexyl)ethynyl]-9-thioxanthenon...)
Show SMILES OC1(CCCCC1)C#Cc1ccc2sc3ccccc3c(=O)c2c1
Show InChI InChI=1S/C21H18O2S/c22-20-16-6-2-3-7-18(16)24-19-9-8-15(14-17(19)20)10-13-21(23)11-4-1-5-12-21/h2-3,6-9,14,23H,1,4-5,11-12H2
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64087((5-methyl-3,6-diphenyl-pyrazolo[1,5-a]pyrimidin-7-...)
Show SMILES Cc1nc2c(cnn2c(N)c1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C19H16N4/c1-13-17(15-10-6-3-7-11-15)18(20)23-19(22-13)16(12-21-23)14-8-4-2-5-9-14/h2-12H,20H2,1H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39001(3-[(4-ethoxyphenoxy)methyl]benzoic acid | MLS00008...)
Show SMILES CCOc1ccc(OCc2cccc(c2)C(O)=O)cc1
Show InChI InChI=1S/C16H16O4/c1-2-19-14-6-8-15(9-7-14)20-11-12-4-3-5-13(10-12)16(17)18/h3-10H,2,11H2,1H3,(H,17,18)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64106(MLS001165977 | N-[4-(4-methyl-1-piperazinyl)phenyl...)
Show SMILES CN1CCN(CC1)c1ccc(NC(=O)N2CCc3ccccc23)cc1
Show InChI InChI=1S/C20H24N4O/c1-22-12-14-23(15-13-22)18-8-6-17(7-9-18)21-20(25)24-11-10-16-4-2-3-5-19(16)24/h2-9H,10-15H2,1H3,(H,21,25)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64111(7-(2-methoxyethyl)-5,6-dimethyl-N-(2-phenylethyl)-...)
Show SMILES COCCn1c(C)c(C)c2c(NCCc3ccccc3)ncnc12
Show InChI InChI=1S/C19H24N4O/c1-14-15(2)23(11-12-24-3)19-17(14)18(21-13-22-19)20-10-9-16-7-5-4-6-8-16/h4-8,13H,9-12H2,1-3H3,(H,20,21,22)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62274(4-tert-butylbenzoic acid [(Z)-[amino(phenyl)methyl...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)ON=C(N)c1ccccc1
Show InChI InChI=1S/C18H20N2O2/c1-18(2,3)15-11-9-14(10-12-15)17(21)22-20-16(19)13-7-5-4-6-8-13/h4-12H,1-3H3,(H2,19,20)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64131(4-tert-butyl-N-[2-(2-fluoranylphenoxy)ethyl]benzam...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)NCCOc1ccccc1F
Show InChI InChI=1S/C19H22FNO2/c1-19(2,3)15-10-8-14(9-11-15)18(22)21-12-13-23-17-7-5-4-6-16(17)20/h4-11H,12-13H2,1-3H3,(H,21,22)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64152(2-(2,3-dihydro-1,4-benzodioxin-3-yl)-5-propylsulfo...)
Show SMILES CCCS(=O)(=O)c1cnc(nc1N)C1COc2ccccc2O1
Show InChI InChI=1S/C15H17N3O4S/c1-2-7-23(19,20)13-8-17-15(18-14(13)16)12-9-21-10-5-3-4-6-11(10)22-12/h3-6,8,12H,2,7,9H2,1H3,(H2,16,17,18)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64157(MLS001175788 | N-(2-phenylethyl)-3,4-dihydro-2H-1,...)
Show SMILES O=C(NCCc1ccccc1)c1ccc2OCCCOc2c1
Show InChI InChI=1S/C18H19NO3/c20-18(19-10-9-14-5-2-1-3-6-14)15-7-8-16-17(13-15)22-12-4-11-21-16/h1-3,5-8,13H,4,9-12H2,(H,19,20)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48017(2,2,2-trifluoro-N-[3-[6-(4-methyl-1-piperidinyl)-3...)
Show SMILES CC1CCN(CC1)c1ccc(nn1)-c1cccc(NC(=O)C(F)(F)F)c1
Show InChI InChI=1S/C18H19F3N4O/c1-12-7-9-25(10-8-12)16-6-5-15(23-24-16)13-3-2-4-14(11-13)22-17(26)18(19,20)21/h2-6,11-12H,7-10H2,1H3,(H,22,26)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63880(1-(tert-butyl)-4-[({[(3,4-dichloroanilino)carbonyl...)
Show SMILES Cc1nn(c(C)c1C=NOC(=O)Nc1ccc(Cl)c(Cl)c1)C(C)(C)C
Show InChI InChI=1S/C17H20Cl2N4O2/c1-10-13(11(2)23(22-10)17(3,4)5)9-20-25-16(24)21-12-6-7-14(18)15(19)8-12/h6-9H,1-5H3,(H,21,24)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36821(1,3-benzodioxol-5-ylmethyl 4-(4-fluorophenyl)-6-me...)
Show SMILES CC1=NC(=O)NC(C1C(=O)OCc1ccc2OCOc2c1)c1ccc(F)cc1
Show InChI InChI=1S/C20H17FN2O5/c1-11-17(18(23-20(25)22-11)13-3-5-14(21)6-4-13)19(24)26-9-12-2-7-15-16(8-12)28-10-27-15/h2-8,17-18H,9-10H2,1H3,(H,23,25)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48112(3-(5-p-cumenyltetrazol-2-yl)propionic acid | 3-[5-...)
Show SMILES CC(C)c1ccc(cc1)-c1nnn(CCC(O)=O)n1
Show InChI InChI=1S/C13H16N4O2/c1-9(2)10-3-5-11(6-4-10)13-14-16-17(15-13)8-7-12(18)19/h3-6,9H,7-8H2,1-2H3,(H,18,19)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38871((2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrah...)
Show SMILES CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc12
Show InChI InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63667(4-(2-fluorophenyl)-2-methylimino-N-[(Z)-2-pyrrolyl...)
Show SMILES CN=c1scc(-c2ccccc2F)n1N=Cc1ccc[nH]1
Show InChI InChI=1S/C15H13FN4S/c1-17-15-20(19-9-11-5-4-8-18-11)14(10-21-15)12-6-2-3-7-13(12)16/h2-10,18H,1H3/b17-15-,19-9+
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63672(MLS001006742 | N'-[(Z)-2-pyrrolylidenemethyl]-4-(8...)
Show SMILES O=C(NN=Cc1ccc[nH]1)c1ccc(COc2cccc3cccnc23)cc1
Show InChI InChI=1S/C22H18N4O2/c27-22(26-25-14-19-6-3-12-23-19)18-10-8-16(9-11-18)15-28-20-7-1-4-17-5-2-13-24-21(17)20/h1-14,23H,15H2,(H,26,27)/b25-14+
Affinity DataEC50:  160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62278(2-bromobenzoic acid [2-[1-(2-methoxyethyl)-2,5-dim...)
Show SMILES COCCn1c(C)cc(C(=O)COC(=O)c2ccccc2Br)c1C
Show InChI InChI=1S/C18H20BrNO4/c1-12-10-15(13(2)20(12)8-9-23-3)17(21)11-24-18(22)14-6-4-5-7-16(14)19/h4-7,10H,8-9,11H2,1-3H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63711(MLS001002830 | N-[3-(dimethylsulfamoyl)-4-methyl-p...)
Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)c2cc3ccccc3oc2=O)ccc1C
Show InChI InChI=1S/C19H18N2O5S/c1-12-8-9-14(11-17(12)27(24,25)21(2)3)20-18(22)15-10-13-6-4-5-7-16(13)26-19(15)23/h4-11H,1-3H3,(H,20,22)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54356(2-bromobenzoic acid [2-[2,5-dimethyl-1-(2-oxolanyl...)
Show SMILES Cc1cc(C(=O)COC(=O)c2ccccc2Br)c(C)n1CC1CCCO1
Show InChI InChI=1S/C20H22BrNO4/c1-13-10-17(14(2)22(13)11-15-6-5-9-25-15)19(23)12-26-20(24)16-7-3-4-8-18(16)21/h3-4,7-8,10,15H,5-6,9,11-12H2,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63719(2-furancarboxylic acid [2-[1-(2-furanylmethyl)-2,5...)
Show SMILES Cc1cc(C(=O)COC(=O)c2ccco2)c(C)n1Cc1ccco1
Show InChI InChI=1S/C18H17NO5/c1-12-9-15(13(2)19(12)10-14-5-3-7-22-14)16(20)11-24-18(21)17-6-4-8-23-17/h3-9H,10-11H2,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM60199(4-[2-[(5-methyl-2-thiophenyl)methylidene]hydraziny...)
Show SMILES Cc1ccc(CN=Nc2ccc(cc2)C(O)=O)s1
Show InChI InChI=1S/C13H12N2O2S/c1-9-2-7-12(18-9)8-14-15-11-5-3-10(4-6-11)13(16)17/h2-7H,8H2,1H3,(H,16,17)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63732(MLS000770511 | N-(4-piperidin-1-ylphenyl)pyridine-...)
Show SMILES O=C(Nc1ccc(cc1)N1CCCCC1)c1ccccn1
Show InChI InChI=1S/C17H19N3O/c21-17(16-6-2-3-11-18-16)19-14-7-9-15(10-8-14)20-12-4-1-5-13-20/h2-3,6-11H,1,4-5,12-13H2,(H,19,21)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63738((2,3-dihydro-1,4-benzodioxin-6-ylmethyleneamino)-(...)
Show SMILES C(N=Nc1ccc2ccccc2n1)c1ccc2OCCOc2c1
Show InChI InChI=1S/C18H15N3O2/c1-2-4-15-14(3-1)6-8-18(20-15)21-19-12-13-5-7-16-17(11-13)23-10-9-22-16/h1-8,11H,9-10,12H2
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36913(2-[(2,5-dimethyl-1-pyridin-2-yl-pyrrol-3-yl)methyl...)
Show SMILES Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccn1
Show InChI InChI=1S/C21H16N4OS/c1-13-11-15(14(2)24(13)19-9-5-6-10-22-19)12-18-20(26)25-17-8-4-3-7-16(17)23-21(25)27-18/h3-12H,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63757(5-(2,3-dihydro-1,4-benzodioxin-6-ylhydrazinylidene...)
Show SMILES O=C1NC(=O)C(=NNc2ccc3OCCOc3c2)C(=O)N1
Show InChI InChI=1S/C12H10N4O5/c17-10-9(11(18)14-12(19)13-10)16-15-6-1-2-7-8(5-6)21-4-3-20-7/h1-2,5,15H,3-4H2,(H2,13,14,17,18,19)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63771((5Z)-5-[(E)-3-phenylprop-2-enylidene]-2-(1-pyrroli...)
Show SMILES O=C1N=C(S\C1=C/C=C/c1ccccc1)N1CCCC1
Show InChI InChI=1S/C16H16N2OS/c19-15-14(10-6-9-13-7-2-1-3-8-13)20-16(17-15)18-11-4-5-12-18/h1-3,6-10H,4-5,11-12H2/b9-6+,14-10-
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52783(2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benzothiazo...)
Show SMILES COC(=O)Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C(C)=Nc1ccccc1
Show InChI InChI=1S/C21H18N4O3S/c1-13(22-14-8-4-3-5-9-14)19-16(12-18(26)28-2)24-25(20(19)27)21-23-15-10-6-7-11-17(15)29-21/h3-11,24H,12H2,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63792(2-(2,4-Dichloro-phenylamino)-4-oxo-4-phenyl-butyri...)
Show SMILES OC(=O)C(CC(=O)c1ccccc1)Nc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C16H13Cl2NO3/c17-11-6-7-13(12(18)8-11)19-14(16(21)22)9-15(20)10-4-2-1-3-5-10/h1-8,14,19H,9H2,(H,21,22)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54380(2-(4-propan-2-ylphenyl)-1,3-benzothiazole | 2-p-cu...)
Show SMILES CC(C)c1ccc(cc1)-c1nc2ccccc2s1
Show InChI InChI=1S/C16H15NS/c1-11(2)12-7-9-13(10-8-12)16-17-14-5-3-4-6-15(14)18-16/h3-11H,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63826(1,3-benzothiazol-2-yl-(2-pyridylmethyleneamino)ami...)
Show SMILES C(N=Nc1nc2ccccc2s1)c1ccccn1
Show InChI InChI=1S/C13H10N4S/c1-2-7-12-11(6-1)16-13(18-12)17-15-9-10-5-3-4-8-14-10/h1-8H,9H2
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63837(2-chloro-4-methyl-benzoic acid [(Z)-[amino(phenyl)...)
Show SMILES Cc1ccc(C(=O)ON=C(N)c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C15H13ClN2O2/c1-10-7-8-12(13(16)9-10)15(19)20-18-14(17)11-5-3-2-4-6-11/h2-9H,1H3,(H2,17,18)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39056(1-(4-chlorophenyl)-4-(3-methyl-1-piperidinyl)pyraz...)
Show SMILES CC1CCCN(C1)c1ncnc2n(ncc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H18ClN5/c1-12-3-2-8-22(10-12)16-15-9-21-23(17(15)20-11-19-16)14-6-4-13(18)5-7-14/h4-7,9,11-12H,2-3,8,10H2,1H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37212(MLS000100814 | N-cyclohexyl-N-methyl-1-(3-methylph...)
Show SMILES CN(C1CCCCC1)c1ncnc2n(ncc12)-c1cccc(C)c1
Show InChI InChI=1S/C19H23N5/c1-14-7-6-10-16(11-14)24-19-17(12-22-24)18(20-13-21-19)23(2)15-8-4-3-5-9-15/h6-7,10-13,15H,3-5,8-9H2,1-2H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54393(2,2-dimethyl-N-[N'-(5-methyl-1,3-benzoxazol-2-yl)a...)
Show SMILES Cc1ccc2oc(N=C(N)NC(=O)C(C)(C)C)nc2c1
Show InChI InChI=1S/C14H18N4O2/c1-8-5-6-10-9(7-8)16-13(20-10)18-12(15)17-11(19)14(2,3)4/h5-7H,1-4H3,(H3,15,16,17,18,19)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63874(5-(7-ethyl-2-imidazo[1,2-a]pyridinyl)-3-phenylisox...)
Show SMILES CCc1ccn2cc(nc2c1)-c1cc(no1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O/c1-2-13-8-9-21-12-16(19-18(21)10-13)17-11-15(20-22-17)14-6-4-3-5-7-14/h3-12H,2H2,1H3
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47995(2-[2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-ket...)
Show SMILES O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccc2OCCCOc2c1
Show InChI InChI=1S/C18H15NO6S/c20-14(12-6-7-15-16(10-12)25-9-3-8-24-15)11-19-18(21)13-4-1-2-5-17(13)26(19,22)23/h1-2,4-7,10H,3,8-9,11H2
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
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