Affinity DataEC50: 0.590nMAssay Description:Agonist activity at rat 5HT4S receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.620nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.650nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at rat 5HT4S receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.960nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at rat 5HT4S receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at recombinant rat 5-HT4L receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase repo...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at recombinant rat 5-HT4L receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase repo...More data for this Ligand-Target Pair
Affinity DataEC50: 6.30nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity in the rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 7.40nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 8.5nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 8.70nMAssay Description:Agonist activity at 5-HT4 receptor in Sprague-Dawley rat oesophagus assessed as relaxation of carbachol precontracted oesophagusMore data for this Ligand-Target Pair
Affinity DataEC50: 9.5nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 9.80nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity in the rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at rat 5-HT4L receptor assessed as cAMP level after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23.7nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at rat 5HT4e receptor expressed in HEK293 cells assessed as cAMP level after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity in the rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Compound was tested against 5-HT4 receptor through agonism of 5-HT mediated relaxation of rat, carbachol contracted esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 40.3nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity in the rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay of racemate mixtureMore data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
