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TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50030815(CHEMBL404594)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to AT2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50030815(CHEMBL404594)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to type-2 angiotensin-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370684(CHEMBL1791349)
Affinity DataKi:  0.180nMpH: 7.4Assay Description:Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370575(CHEMBL1791308)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370575(CHEMBL1791308)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50009338((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(d...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to type-2 angiotensin-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50009338((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(d...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to AT2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to AT2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to type-2 angiotensin-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to AT2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to AT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199311(CHEMBL215160 | N-butyloxycarbonyl-2-(4-imidazol-1-...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156167(CHEMBL361927 | butyl (5-isobutylthien-2-yl)sulfony...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199326(CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50139783(Angiotensin II analogue | CHEMBL404996)
Affinity DataKi:  0.620nMAssay Description:Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370686(CHEMBL1791350)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199326(CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370375(CHEMBL268815)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199326(CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to type-2 angiotensin-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50168428((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)
Affinity DataKi:  0.898nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM410295(US10370388, Compound Angiotensin)
Affinity DataKi:  0.898nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370375(CHEMBL268815)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50208102(CHEMBL424755 | [4-NH2-Phe6] Ang II)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrial membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156176((2S,5R,7aR)-6-[2-((S)-Acetylamino)-3-methyl-butyry...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-Ang II from pig uterus myometrium angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199331(CHEMBL216250 | N-(1-butyloxy-methylcarbonyl)-3-(4-...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50594171(CHEMBL5186237)
Affinity DataKi:  1.20nMAssay Description:Displacement of 125I-[Sar1,Ile8]ANGII form recombinant human full length AT2 receptor expressed in HEK293 cells incubated for 120 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370375(CHEMBL268815)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-Ang II from pig uterus myometrium angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50594186(CHEMBL5174659)
Affinity DataKi:  1.40nMAssay Description:Displacement of 125I-[Sar1,Ile8]ANGII form recombinant human full length AT2 receptor expressed in HEK293 cells incubated for 120 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50049195(3-[(2'-(butylsulfonylcarbamate)-3'-propyl-1,1'-bip...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50195697((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-2-[(2S)-bu...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)
Affinity DataKi:  1.80nMAssay Description:Agonist activity at AT2 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50175584((S)-3-Amino-N-((S)-1-{1-[(S)-3-[2-[2-((S)-(S)-1-ca...)
Affinity DataKi:  1.85nMpH: 7.4Assay Description:Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50199317(CHEMBL214525 | N-ethyloxycarbonyl-2-(4-imidazol-1-...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]Ang2 from AT2 receptor in pig uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50049189(3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...)
Affinity DataKi:  2nMAssay Description:Displacement of 125I-[Sar1,Ile8]ANGII form AT2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50141059(CHEMBL289614 | L-162782 | N-Butyloxycarbonyl-4'-(2...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156178(CHEMBL216331 | c[Hcy3,5]Ang II)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]-Ang II from pig uterus myometrium angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370375(CHEMBL268815)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370576(CHEMBL1791309)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50370576(CHEMBL1791309)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50594170(CHEMBL5174923)
Affinity DataKi:  2.70nMAssay Description:Displacement of 125I-[Sar1,Ile8]ANGII form recombinant human full length AT2 receptor expressed in HEK293 cells incubated for 120 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50168424((3S)-3-amino-3-{[(1S)-1-{[(2S)-4-({[(2S)-1-[(2S)-2...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50049189(3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50049189(3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50139787((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...)
Affinity DataKi:  3nMAssay Description:Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50139787((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50156172(CHEMBL190577 | butyl (5-isobutylthien-2-yl)sulfony...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50594187(CHEMBL5179119)
Affinity DataKi:  3.20nMAssay Description:Displacement of 125I-[Sar1,Ile8]ANGII form recombinant human full length AT2 receptor expressed in HEK293 cells incubated for 120 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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