Compile Data Set for Download or QSAR
Report error Found 1600 of ic50 for UniProtKB: P25101
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141472((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamin...)
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141458((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141472((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamin...)
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141458((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141475((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0140nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141465((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50: 0.0220nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155246(CHEMBL3775234)
Affinity DataIC50: 0.0230nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cells measured after 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 0.0230nMAssay Description:Displacement of [125I]-endothelin-1 from human recombinant ETA receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155246(CHEMBL3775234)
Affinity DataIC50: 0.0230nMAssay Description:Displacement of [125I]Endothelin-1 from human recombinant Endothelin-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141468((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-dimethy...)
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141468((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-dimethy...)
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141471((5S,6R,7R)-7-{2-[(Acetyl-methyl-amino)-methyl]-4-m...)
Affinity DataIC50: 0.0270nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141463((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0310nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.0340nMAssay Description:Ability to displace endothelin ([125I]ET1) from human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.0340nMAssay Description:Binding ability determined by the displacement of [125I]ET1 from the human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098777(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061096((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(butane-1...)
Affinity DataIC50: 0.0440nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000558(Endothelin-1 | ET-1 | Endothelin -1 | c(Cys-Ser-c(...)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of ETA receptor in human SK-N-MC cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141470((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2,4-dimethox...)
Affinity DataIC50: 0.0470nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141461((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2,3-dihyd...)
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141461((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2,3-dihyd...)
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077930(5-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061078((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-m...)
Affinity DataIC50: 0.0550nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.0550nMAssay Description:Displacement of [125I]ET-1 from human ET-A receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141467((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141467((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy...)
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141460((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141460((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141473((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-hydroxymet...)
Affinity DataIC50: 0.0620nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141457((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061086((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro...)
Affinity DataIC50: 0.0700nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061085((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-m...)
Affinity DataIC50: 0.0770nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061074((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-m...)
Affinity DataIC50: 0.0780nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061074((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-m...)
Affinity DataIC50: 0.0800nMAssay Description:Binding affinity towards human Endothelin A receptor (hET -A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.0800nMAssay Description:Binding affinity towards human Endothelin A receptor (hET -A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077933(4-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50532581(CHEMBL4467748)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-ET-1 from human ETA receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098780(3-(4-Chloro-5-methyl-isoxazol-3-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119678((R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamino-7-(4-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50532581(CHEMBL4467748)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-ET-1 from human ETA receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329839(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]ET1 from ETA receptor expressed in african green monkey CCL-81 cells monolayerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141459((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-isopropoxy...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050976(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.110nMAssay Description:Radioligand binding selectivity to human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057169(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119676((R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2...)
Affinity DataIC50: 0.120nMAssay Description:Inhibitory activity against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098773(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.120nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098778(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061085((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-m...)
Affinity DataIC50: 0.140nMAssay Description:Ability to block the ET-1-induced hydrolysis of inositol phosphate in Endothelin A receptor of MMQ cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098774(2-[2-(3-Hydroxy-2,4,6-trimethyl-phenyl)-acetyl]-th...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066379((2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataIC50: 0.170nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]ET1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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