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Found 6 of ec50 for UniProtKB: A0A1U9X7R0
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM86283(CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation at human GABA-B 1b expressed in CHO cells co-expressing rat GABA-B2 assessed as potentiation of GABA-induced inhibitio...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50243872((+/-)-4-Amino-1-cyclopent-1-enyl(methyl)phosphinic...)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50243874((+)-(S)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...)
Affinity DataEC50:  5.22E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50243873((-)-(R)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...)
Affinity DataEC50:  7.19E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataEC50:  5.00E+5nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed