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Report error Found 112 of ec50 for UniProtKB: P06536
TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153512((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153512((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...)
Affinity DataEC50:  0.200nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153512((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...)
Affinity DataEC50:  0.300nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50577695(CHEMBL4853394)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50594604(CHEMBL5173367)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)
Affinity DataEC50:  0.760nMAssay Description:Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosine amino transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50594607(CHEMBL5185246)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153501((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  1.70nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153508(Benzo[b]thiophen-3-yl-[(4aR,5S)-1-(4-fluoro-phenyl...)
Affinity DataEC50:  1.80nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataEC50:  2.5nMAssay Description:Binding affinity to rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153504(CHEMBL366093 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  3nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153509(CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  3nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153503(3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...)
Affinity DataEC50:  3nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153502(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  3nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153503(3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...)
Affinity DataEC50:  3nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153503(3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...)
Affinity DataEC50:  3nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153501((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  3nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153513(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  3nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153507(CHEMBL186948 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  3nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153506((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  3nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153509(CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  3nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153519(CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  3nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153509(CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  4nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153506((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  4nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153519(CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153515(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  4nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50577692(CHEMBL4872787)
Affinity DataEC50:  4nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50577690(CHEMBL4855992)
Affinity DataEC50:  4nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153504(CHEMBL366093 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153515(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153502(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  5nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153515(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  6nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50577691(CHEMBL4850526)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153513(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  7nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50577710(CHEMBL4857046)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50107347((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Affinity DataEC50:  7.90nMAssay Description:Binding affinity to rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153519(CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...)
Affinity DataEC50:  8nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153502(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  8nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153501((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  8nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153511(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153506((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153511(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  11nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153513(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153514(4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...)
Affinity DataEC50:  12nMAssay Description:Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153514(4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...)
Affinity DataEC50:  16nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM19201((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50153511(1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...)
Affinity DataEC50:  17nMAssay Description:Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50357083(CHEMBL1917414)
Affinity DataEC50:  18.7nMAssay Description:Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosine amino transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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