Compile Data Set for Download or QSAR
maximum 50k data
Found 586 of ic50 for UniProtKB: P25929
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091652(CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YP...)
Affinity DataIC50:  0.0200nMAssay Description:Affinity against Neuropeptide Y receptor Y1 in SK-N-MC cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.0501nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.0501nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 30 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553107(CHEMBL4746035)
Affinity DataIC50:  0.0550nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553111(CHEMBL4786911)
Affinity DataIC50:  0.0617nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.0631nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553117(CHEMBL4755692)
Affinity DataIC50:  0.0661nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.0700nMAssay Description:Binding affinity to human neuropeptide Y1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553110(CHEMBL4794692)
Affinity DataIC50:  0.0794nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553113(CHEMBL4798118)
Affinity DataIC50:  0.0912nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 30 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50:  0.105nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553108(CHEMBL4743858)
Affinity DataIC50:  0.110nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataIC50:  0.120nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553109(CHEMBL4751322)
Affinity DataIC50:  0.126nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.126nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.129nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301193(6-((5-ethyl-4-(fluoromethyl)thiazol-2-ylthio)methy...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]peptide YY from human Y1 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.140nMAssay Description:Binding affinity to human neuropeptide Y receptor type 1 by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50:  0.151nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.151nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301204(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-meth...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50:  0.162nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.170nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.170nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.170nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553114(CHEMBL4753520)
Affinity DataIC50:  0.186nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500153(CHEMBL3746851)
Affinity DataIC50:  0.195nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50208988(HUMAN NEUROPEPTIDE Y)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [125I]peptide YY from Y1 receptor in human SK-N-MC cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500153(CHEMBL3746851)
Affinity DataIC50:  0.219nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataIC50:  0.240nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553119(CHEMBL4745338)
Affinity DataIC50:  0.240nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553120(CHEMBL4762044)
Affinity DataIC50:  0.240nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301209(6-((4,5-dimethylthiazol-2-ylthio)methyl)-N-((6-met...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301203(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-fluo...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553112(CHEMBL4752935)
Affinity DataIC50:  0.282nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.324nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50:  0.331nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500153(CHEMBL3746851)
Affinity DataIC50:  0.347nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301207(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-N-((6-...)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50553116(CHEMBL4789673)
Affinity DataIC50:  0.407nMAssay Description:Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50:  0.417nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50:  0.427nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50301208(CHEMBL566040 | N-((6-methylpyridin-2-yl)methyl)-4-...)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataIC50:  0.479nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 1 min by Fura-2 dye based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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